Efficient protein production by yeast requires global tuning of metabolism

The contribution of metabolic pathways to protein secretion is largely unknown. Here, the authors find conserved metabolic patterns in yeast by examining genome-wide transcriptional responses in high protein secretion mutants and reveal critical factors that can be tuned for efficient protein secret...

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Autores principales:	Mingtao Huang, Jichen Bao, Björn M. Hallström, Dina Petranovic, Jens Nielsen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f678b36925754173ae342618040dbd75
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id	oai:doaj.org-article:f678b36925754173ae342618040dbd75
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spelling	oai:doaj.org-article:f678b36925754173ae342618040dbd752021-12-02T14:40:23ZEfficient protein production by yeast requires global tuning of metabolism10.1038/s41467-017-00999-22041-1723https://doaj.org/article/f678b36925754173ae342618040dbd752017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00999-2https://doaj.org/toc/2041-1723The contribution of metabolic pathways to protein secretion is largely unknown. Here, the authors find conserved metabolic patterns in yeast by examining genome-wide transcriptional responses in high protein secretion mutants and reveal critical factors that can be tuned for efficient protein secretion.Mingtao HuangJichen BaoBjörn M. HallströmDina PetranovicJens NielsenNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Mingtao Huang Jichen Bao Björn M. Hallström Dina Petranovic Jens Nielsen Efficient protein production by yeast requires global tuning of metabolism
description	The contribution of metabolic pathways to protein secretion is largely unknown. Here, the authors find conserved metabolic patterns in yeast by examining genome-wide transcriptional responses in high protein secretion mutants and reveal critical factors that can be tuned for efficient protein secretion.
format	article
author	Mingtao Huang Jichen Bao Björn M. Hallström Dina Petranovic Jens Nielsen
author_facet	Mingtao Huang Jichen Bao Björn M. Hallström Dina Petranovic Jens Nielsen
author_sort	Mingtao Huang
title	Efficient protein production by yeast requires global tuning of metabolism
title_short	Efficient protein production by yeast requires global tuning of metabolism
title_full	Efficient protein production by yeast requires global tuning of metabolism
title_fullStr	Efficient protein production by yeast requires global tuning of metabolism
title_full_unstemmed	Efficient protein production by yeast requires global tuning of metabolism
title_sort	efficient protein production by yeast requires global tuning of metabolism
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/f678b36925754173ae342618040dbd75
work_keys_str_mv	AT mingtaohuang efficientproteinproductionbyyeastrequiresglobaltuningofmetabolism AT jichenbao efficientproteinproductionbyyeastrequiresglobaltuningofmetabolism AT bjornmhallstrom efficientproteinproductionbyyeastrequiresglobaltuningofmetabolism AT dinapetranovic efficientproteinproductionbyyeastrequiresglobaltuningofmetabolism AT jensnielsen efficientproteinproductionbyyeastrequiresglobaltuningofmetabolism
_version_	1718390333513924608

Efficient protein production by yeast requires global tuning of metabolism

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