Efficient protein production by yeast requires global tuning of metabolism

The contribution of metabolic pathways to protein secretion is largely unknown. Here, the authors find conserved metabolic patterns in yeast by examining genome-wide transcriptional responses in high protein secretion mutants and reveal critical factors that can be tuned for efficient protein secret...

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Autores principales: Mingtao Huang, Jichen Bao, Björn M. Hallström, Dina Petranovic, Jens Nielsen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/f678b36925754173ae342618040dbd75
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