Identification of the elementary structural units of the DNA damage response
Phosphorylated histone H2AX is an early signalling event of DNA double-strand breaks. Here the authors use super-resolution microscopy and ChIP-seq and identify ‘nano-domains’ – chromatin loops decorated by γH2AX and flanked by CTCF.
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Nature Portfolio
2017
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oai:doaj.org-article:f68ca12edcb14f05a6eb4fd6ba45d0ae2021-12-02T14:41:21ZIdentification of the elementary structural units of the DNA damage response10.1038/ncomms157602041-1723https://doaj.org/article/f68ca12edcb14f05a6eb4fd6ba45d0ae2017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15760https://doaj.org/toc/2041-1723Phosphorylated histone H2AX is an early signalling event of DNA double-strand breaks. Here the authors use super-resolution microscopy and ChIP-seq and identify ‘nano-domains’ – chromatin loops decorated by γH2AX and flanked by CTCF.Francesco NataleAlexander RappWei YuAndreas MaiserHartmann HarzAnnina SchollStephan GrulichTobias AntonDavid HörlWei ChenMarco DuranteGisela Taucher-ScholzHeinrich LeonhardtM. Cristina CardosoNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-18 (2017) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Francesco Natale Alexander Rapp Wei Yu Andreas Maiser Hartmann Harz Annina Scholl Stephan Grulich Tobias Anton David Hörl Wei Chen Marco Durante Gisela Taucher-Scholz Heinrich Leonhardt M. Cristina Cardoso Identification of the elementary structural units of the DNA damage response |
| description |
Phosphorylated histone H2AX is an early signalling event of DNA double-strand breaks. Here the authors use super-resolution microscopy and ChIP-seq and identify ‘nano-domains’ – chromatin loops decorated by γH2AX and flanked by CTCF. |
| format |
article |
| author |
Francesco Natale Alexander Rapp Wei Yu Andreas Maiser Hartmann Harz Annina Scholl Stephan Grulich Tobias Anton David Hörl Wei Chen Marco Durante Gisela Taucher-Scholz Heinrich Leonhardt M. Cristina Cardoso |
| author_facet |
Francesco Natale Alexander Rapp Wei Yu Andreas Maiser Hartmann Harz Annina Scholl Stephan Grulich Tobias Anton David Hörl Wei Chen Marco Durante Gisela Taucher-Scholz Heinrich Leonhardt M. Cristina Cardoso |
| author_sort |
Francesco Natale |
| title |
Identification of the elementary structural units of the DNA damage response |
| title_short |
Identification of the elementary structural units of the DNA damage response |
| title_full |
Identification of the elementary structural units of the DNA damage response |
| title_fullStr |
Identification of the elementary structural units of the DNA damage response |
| title_full_unstemmed |
Identification of the elementary structural units of the DNA damage response |
| title_sort |
identification of the elementary structural units of the dna damage response |
| publisher |
Nature Portfolio |
| publishDate |
2017 |
| url |
https://doaj.org/article/f68ca12edcb14f05a6eb4fd6ba45d0ae |
| work_keys_str_mv |
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| _version_ |
1718389967802073088 |