Identification of the elementary structural units of the DNA damage response

Phosphorylated histone H2AX is an early signalling event of DNA double-strand breaks. Here the authors use super-resolution microscopy and ChIP-seq and identify ‘nano-domains’ – chromatin loops decorated by γH2AX and flanked by CTCF.

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Bibliographic Details
Main Authors:	Francesco Natale, Alexander Rapp, Wei Yu, Andreas Maiser, Hartmann Harz, Annina Scholl, Stephan Grulich, Tobias Anton, David Hörl, Wei Chen, Marco Durante, Gisela Taucher-Scholz, Heinrich Leonhardt, M. Cristina Cardoso
Format:	article
Language:	EN
Published:	Nature Portfolio 2017
Subjects:	Science Q
Online Access:	https://doaj.org/article/f68ca12edcb14f05a6eb4fd6ba45d0ae
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spelling	oai:doaj.org-article:f68ca12edcb14f05a6eb4fd6ba45d0ae2021-12-02T14:41:21ZIdentification of the elementary structural units of the DNA damage response10.1038/ncomms157602041-1723https://doaj.org/article/f68ca12edcb14f05a6eb4fd6ba45d0ae2017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15760https://doaj.org/toc/2041-1723Phosphorylated histone H2AX is an early signalling event of DNA double-strand breaks. Here the authors use super-resolution microscopy and ChIP-seq and identify ‘nano-domains’ – chromatin loops decorated by γH2AX and flanked by CTCF.Francesco NataleAlexander RappWei YuAndreas MaiserHartmann HarzAnnina SchollStephan GrulichTobias AntonDavid HörlWei ChenMarco DuranteGisela Taucher-ScholzHeinrich LeonhardtM. Cristina CardosoNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Francesco Natale Alexander Rapp Wei Yu Andreas Maiser Hartmann Harz Annina Scholl Stephan Grulich Tobias Anton David Hörl Wei Chen Marco Durante Gisela Taucher-Scholz Heinrich Leonhardt M. Cristina Cardoso Identification of the elementary structural units of the DNA damage response
description	Phosphorylated histone H2AX is an early signalling event of DNA double-strand breaks. Here the authors use super-resolution microscopy and ChIP-seq and identify ‘nano-domains’ – chromatin loops decorated by γH2AX and flanked by CTCF.
format	article
author	Francesco Natale Alexander Rapp Wei Yu Andreas Maiser Hartmann Harz Annina Scholl Stephan Grulich Tobias Anton David Hörl Wei Chen Marco Durante Gisela Taucher-Scholz Heinrich Leonhardt M. Cristina Cardoso
author_facet	Francesco Natale Alexander Rapp Wei Yu Andreas Maiser Hartmann Harz Annina Scholl Stephan Grulich Tobias Anton David Hörl Wei Chen Marco Durante Gisela Taucher-Scholz Heinrich Leonhardt M. Cristina Cardoso
author_sort	Francesco Natale
title	Identification of the elementary structural units of the DNA damage response
title_short	Identification of the elementary structural units of the DNA damage response
title_full	Identification of the elementary structural units of the DNA damage response
title_fullStr	Identification of the elementary structural units of the DNA damage response
title_full_unstemmed	Identification of the elementary structural units of the DNA damage response
title_sort	identification of the elementary structural units of the dna damage response
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/f68ca12edcb14f05a6eb4fd6ba45d0ae
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Identification of the elementary structural units of the DNA damage response

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