Identification of the elementary structural units of the DNA damage response
Phosphorylated histone H2AX is an early signalling event of DNA double-strand breaks. Here the authors use super-resolution microscopy and ChIP-seq and identify ‘nano-domains’ – chromatin loops decorated by γH2AX and flanked by CTCF.
Enregistré dans:
Auteurs principaux: | Francesco Natale, Alexander Rapp, Wei Yu, Andreas Maiser, Hartmann Harz, Annina Scholl, Stephan Grulich, Tobias Anton, David Hörl, Wei Chen, Marco Durante, Gisela Taucher-Scholz, Heinrich Leonhardt, M. Cristina Cardoso |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2017
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/f68ca12edcb14f05a6eb4fd6ba45d0ae |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Desmoglein 2 regulates the intestinal epithelial barrier via p38 mitogen-activated protein kinase
par: Hanna Ungewiß, et autres
Publié: (2017) -
Cohesin depleted cells rebuild functional nuclear compartments after endomitosis
par: Marion Cremer, et autres
Publié: (2020) - Elementary STEM Journal
-
The elementary school journal
Publié: (1914) -
The Elementary Particles of Quantum Fields
par: Gregg Jaeger
Publié: (2021)