Programmable sequential mutagenesis by inducible Cpf1 crRNA array inversion

Few models recapitulate the stepwise nature of cancer evolution. Here the authors introduce Cpf1-Flip, a system to introduce mutations sequentially through inducible inversion of a crRNA array.

Guardado en:

Detalles Bibliográficos
Autores principales:	Ryan D. Chow, Hyunu Ray Kim, Sidi Chen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f68de208a0314050b6bbd0049099b092
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:f68de208a0314050b6bbd0049099b092
record_format	dspace
spelling	oai:doaj.org-article:f68de208a0314050b6bbd0049099b0922021-12-02T14:39:11ZProgrammable sequential mutagenesis by inducible Cpf1 crRNA array inversion10.1038/s41467-018-04158-z2041-1723https://doaj.org/article/f68de208a0314050b6bbd0049099b0922018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04158-zhttps://doaj.org/toc/2041-1723Few models recapitulate the stepwise nature of cancer evolution. Here the authors introduce Cpf1-Flip, a system to introduce mutations sequentially through inducible inversion of a crRNA array.Ryan D. ChowHyunu Ray KimSidi ChenNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ryan D. Chow Hyunu Ray Kim Sidi Chen Programmable sequential mutagenesis by inducible Cpf1 crRNA array inversion
description	Few models recapitulate the stepwise nature of cancer evolution. Here the authors introduce Cpf1-Flip, a system to introduce mutations sequentially through inducible inversion of a crRNA array.
format	article
author	Ryan D. Chow Hyunu Ray Kim Sidi Chen
author_facet	Ryan D. Chow Hyunu Ray Kim Sidi Chen
author_sort	Ryan D. Chow
title	Programmable sequential mutagenesis by inducible Cpf1 crRNA array inversion
title_short	Programmable sequential mutagenesis by inducible Cpf1 crRNA array inversion
title_full	Programmable sequential mutagenesis by inducible Cpf1 crRNA array inversion
title_fullStr	Programmable sequential mutagenesis by inducible Cpf1 crRNA array inversion
title_full_unstemmed	Programmable sequential mutagenesis by inducible Cpf1 crRNA array inversion
title_sort	programmable sequential mutagenesis by inducible cpf1 crrna array inversion
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/f68de208a0314050b6bbd0049099b092
work_keys_str_mv	AT ryandchow programmablesequentialmutagenesisbyinduciblecpf1crrnaarrayinversion AT hyunuraykim programmablesequentialmutagenesisbyinduciblecpf1crrnaarrayinversion AT sidichen programmablesequentialmutagenesisbyinduciblecpf1crrnaarrayinversion
_version_	1718390748941910016

Programmable sequential mutagenesis by inducible Cpf1 crRNA array inversion

Ejemplares similares