Live-cell imaging reveals the relative contributions of antigen-presenting cell subsets to thymic central tolerance
Both thymic epithelial cells and dendritic cells present self antigens in the thymus to mediate thymic selection and T cell tolerance. Here the authors quantify, using two-photon live imaging of mouse thymic slices, the relative contribution of these two cell types, as well as the effects of antigen...
Guardado en:
Autores principales: | J. N. Lancaster, H. M. Thyagarajan, J. Srinivasan, Y. Li, Z. Hu, L. I. R. Ehrlich |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/f690393b9d224291a50a4eb2bf28dd24 |
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