Live-cell imaging reveals the relative contributions of antigen-presenting cell subsets to thymic central tolerance

Both thymic epithelial cells and dendritic cells present self antigens in the thymus to mediate thymic selection and T cell tolerance. Here the authors quantify, using two-photon live imaging of mouse thymic slices, the relative contribution of these two cell types, as well as the effects of antigen...

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Autores principales: J. N. Lancaster, H. M. Thyagarajan, J. Srinivasan, Y. Li, Z. Hu, L. I. R. Ehrlich
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/f690393b9d224291a50a4eb2bf28dd24
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