First Case of Cancrum Oris (Noma) in an HIV-Positive Patient in Bulgaria

We present a case of a necrotising disease of the orofacial tissues, the so-called noma, in a female patient with AIDS in a stage of severe immune deficiency. To our knowledge, this is the first time a case like that has been reported in Bulgaria. The patient received an antibiotic course of treatme...

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Autores principales: Grozdeva R., Strashimirov D., Timchev A., Tchervenyakova T., Yancheva N.
Formato: article
Lenguaje:EN
Publicado: Sciendo 2020
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Acceso en línea:https://doaj.org/article/f690852fea2f40ddbd9c38cdcbfbdab9
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Sumario:We present a case of a necrotising disease of the orofacial tissues, the so-called noma, in a female patient with AIDS in a stage of severe immune deficiency. To our knowledge, this is the first time a case like that has been reported in Bulgaria. The patient received an antibiotic course of treatment with a triple combination to good effect on the inflammatory process, and began also HAART. Within 3 weeks, the patient’s general condition improved. However, despite the treatment, a demarcation line was formed, and a defect on the lower lip occurred. Noma is a manifestation of severe immune deficiency with lasting adverse consequences for the patient: severe deformation of the maxilo-facial region and functional impairment (i.e. difficulties eating and speaking, and salivary leak).