The structural basis of proton driven zinc transport by ZntB

The bacterial zinc transporter ZntB is important for maintaining zinc homeostasis and is mechanistically not well understood. Here, the authors present the cryo-EM structure of ZntB at 4.2 Å resolution, perform transport assays and propose a model for its Zn2+ transport mechanism.

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Autores principales:	Cornelius Gati, Artem Stetsenko, Dirk J. Slotboom, Sjors H. W. Scheres, Albert Guskov
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f69903bf49634f44a8aac6aecf07c222
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id	oai:doaj.org-article:f69903bf49634f44a8aac6aecf07c222
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spelling	oai:doaj.org-article:f69903bf49634f44a8aac6aecf07c2222021-12-02T15:37:03ZThe structural basis of proton driven zinc transport by ZntB10.1038/s41467-017-01483-72041-1723https://doaj.org/article/f69903bf49634f44a8aac6aecf07c2222017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01483-7https://doaj.org/toc/2041-1723The bacterial zinc transporter ZntB is important for maintaining zinc homeostasis and is mechanistically not well understood. Here, the authors present the cryo-EM structure of ZntB at 4.2 Å resolution, perform transport assays and propose a model for its Zn2+ transport mechanism.Cornelius GatiArtem StetsenkoDirk J. SlotboomSjors H. W. ScheresAlbert GuskovNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Cornelius Gati Artem Stetsenko Dirk J. Slotboom Sjors H. W. Scheres Albert Guskov The structural basis of proton driven zinc transport by ZntB
description	The bacterial zinc transporter ZntB is important for maintaining zinc homeostasis and is mechanistically not well understood. Here, the authors present the cryo-EM structure of ZntB at 4.2 Å resolution, perform transport assays and propose a model for its Zn2+ transport mechanism.
format	article
author	Cornelius Gati Artem Stetsenko Dirk J. Slotboom Sjors H. W. Scheres Albert Guskov
author_facet	Cornelius Gati Artem Stetsenko Dirk J. Slotboom Sjors H. W. Scheres Albert Guskov
author_sort	Cornelius Gati
title	The structural basis of proton driven zinc transport by ZntB
title_short	The structural basis of proton driven zinc transport by ZntB
title_full	The structural basis of proton driven zinc transport by ZntB
title_fullStr	The structural basis of proton driven zinc transport by ZntB
title_full_unstemmed	The structural basis of proton driven zinc transport by ZntB
title_sort	structural basis of proton driven zinc transport by zntb
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/f69903bf49634f44a8aac6aecf07c222
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The structural basis of proton driven zinc transport by ZntB

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