Management of Inflamed Conjunctival Nevus with Topical Antiallergic Medications: Case Series

Kumiko Kato,1 Maki Takeuchi,1 Yuka Yonekawa,1 Yuzen Kashima,1 Koji Hirano,2 Mineo Kondo1 1Department of Ophthalmology, Mie University Graduate School of Medicine, Tsu, Japan; 2Department of Ophthalmology, Fujita Health University Bantane Hospital, Nagoya, JapanCorrespondence: Kumiko KatoDepartment o...

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Autores principales:	Kato K, Takeuchi M, Yonekawa Y, Kashima Y, Hirano K, Kondo M
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	inflamed juvenile conjunctival nevus epinastine tacrolimus Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/f69aa169b8a847d28fda2c49809bf773
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spelling	oai:doaj.org-article:f69aa169b8a847d28fda2c49809bf7732021-12-02T14:14:47ZManagement of Inflamed Conjunctival Nevus with Topical Antiallergic Medications: Case Series1177-5483https://doaj.org/article/f69aa169b8a847d28fda2c49809bf7732021-02-01T00:00:00Zhttps://www.dovepress.com/management-of-inflamed-conjunctival-nevus-with-topical-antiallergic-me-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Kumiko Kato,1 Maki Takeuchi,1 Yuka Yonekawa,1 Yuzen Kashima,1 Koji Hirano,2 Mineo Kondo1 1Department of Ophthalmology, Mie University Graduate School of Medicine, Tsu, Japan; 2Department of Ophthalmology, Fujita Health University Bantane Hospital, Nagoya, JapanCorrespondence: Kumiko KatoDepartment of Ophthalmology, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, JapanTel +81-59-231-5027Fax +81-59-231-3036Email k-kato@clin.medic.mie-u.ac.jpPurpose: To report our findings in three cases of an inflamed conjunctival nevus whose size and degree of pigmentation were reduced by topical antiallergic and immunosuppressive ophthalmic solutions.Methods: Observational case series. Three patients with inflamed conjunctival nevus were examined by slit-lamp biomicroscopy, and the findings before and after the treatments were compared.Results: All three patients had a slightly pigmented and edematous conjunctival tumor at the corneal limbal area. The tumors were hyperemic, and papillae and follicles were present on the superior conjunctiva in all patients. All of the patients had an allergic predisposition. The antiallergic treatment not only resolved the hyperemia and edema of the palpebral conjunctiva, but also reduced the tumor size. In one case, the topical antiallergic agent alone led to a reduction of the tumor size. A combination of topical antiallergic agent and topical immunosuppressant was effective in reducing the tumor size and degree of pigmentation in the other two patients.Conclusion: The hyperemia and pigmentation in eyes with inflamed conjunctival nevus can be resolved by topical antiallergic agent and topical immunosuppressant without resection of the tumor.Keywords: inflamed juvenile conjunctival nevus, epinastine, tacrolimusKato KTakeuchi MYonekawa YKashima YHirano KKondo MDove Medical Pressarticleinflamed juvenile conjunctival nevusepinastinetacrolimusOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 15, Pp 559-564 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	inflamed juvenile conjunctival nevus epinastine tacrolimus Ophthalmology RE1-994
spellingShingle	inflamed juvenile conjunctival nevus epinastine tacrolimus Ophthalmology RE1-994 Kato K Takeuchi M Yonekawa Y Kashima Y Hirano K Kondo M Management of Inflamed Conjunctival Nevus with Topical Antiallergic Medications: Case Series
description	Kumiko Kato,1 Maki Takeuchi,1 Yuka Yonekawa,1 Yuzen Kashima,1 Koji Hirano,2 Mineo Kondo1 1Department of Ophthalmology, Mie University Graduate School of Medicine, Tsu, Japan; 2Department of Ophthalmology, Fujita Health University Bantane Hospital, Nagoya, JapanCorrespondence: Kumiko KatoDepartment of Ophthalmology, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, JapanTel +81-59-231-5027Fax +81-59-231-3036Email k-kato@clin.medic.mie-u.ac.jpPurpose: To report our findings in three cases of an inflamed conjunctival nevus whose size and degree of pigmentation were reduced by topical antiallergic and immunosuppressive ophthalmic solutions.Methods: Observational case series. Three patients with inflamed conjunctival nevus were examined by slit-lamp biomicroscopy, and the findings before and after the treatments were compared.Results: All three patients had a slightly pigmented and edematous conjunctival tumor at the corneal limbal area. The tumors were hyperemic, and papillae and follicles were present on the superior conjunctiva in all patients. All of the patients had an allergic predisposition. The antiallergic treatment not only resolved the hyperemia and edema of the palpebral conjunctiva, but also reduced the tumor size. In one case, the topical antiallergic agent alone led to a reduction of the tumor size. A combination of topical antiallergic agent and topical immunosuppressant was effective in reducing the tumor size and degree of pigmentation in the other two patients.Conclusion: The hyperemia and pigmentation in eyes with inflamed conjunctival nevus can be resolved by topical antiallergic agent and topical immunosuppressant without resection of the tumor.Keywords: inflamed juvenile conjunctival nevus, epinastine, tacrolimus
format	article
author	Kato K Takeuchi M Yonekawa Y Kashima Y Hirano K Kondo M
author_facet	Kato K Takeuchi M Yonekawa Y Kashima Y Hirano K Kondo M
author_sort	Kato K
title	Management of Inflamed Conjunctival Nevus with Topical Antiallergic Medications: Case Series
title_short	Management of Inflamed Conjunctival Nevus with Topical Antiallergic Medications: Case Series
title_full	Management of Inflamed Conjunctival Nevus with Topical Antiallergic Medications: Case Series
title_fullStr	Management of Inflamed Conjunctival Nevus with Topical Antiallergic Medications: Case Series
title_full_unstemmed	Management of Inflamed Conjunctival Nevus with Topical Antiallergic Medications: Case Series
title_sort	management of inflamed conjunctival nevus with topical antiallergic medications: case series
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/f69aa169b8a847d28fda2c49809bf773
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Management of Inflamed Conjunctival Nevus with Topical Antiallergic Medications: Case Series

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