Induction of differentiation of intrahepatic cholangiocarcinoma cells to functional hepatocytes using an organoid culture system
Abstract Intrahepatic cholangiocarcinoma (IHCC) is a highly aggressive malignancy with a poor prognosis. It is thought to originate from cholangiocytes, which are the component cells of intrahepatic bile ducts. However, as patients with viral hepatitis often develop IHCC, it has been suggested that...
Guardado en:
Autores principales: | Yoshimasa Saito, Toshiaki Nakaoka, Toshihide Muramatsu, Hidenori Ojima, Aoi Sukeda, Yuko Sugiyama, Ryoei Uchida, Ryo Furukawa, Aya Kitahara, Toshiro Sato, Yae Kanai, Hidetsugu Saito |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/f69bc81672bf4ab595b91a7b1a8952f1 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Epigenetic silencing of Lgr5 induces senescence of intestinal epithelial organoids during the process of aging
por: Ryoei Uchida, et al.
Publicado: (2018) -
Publisher Correction: Epigenetic silencing of Lgr5 induces senescence of intestinal epithelial organoids during the process of aging
por: Ryoei Uchida, et al.
Publicado: (2019) -
Challenges and Opportunities for Treating Intrahepatic Cholangiocarcinoma
por: Serifis N, et al.
Publicado: (2021) -
TGF-β1 expression is associated with invasion and metastasis of intrahepatic cholangiocarcinoma
por: Chen,Yijie, et al.
Publicado: (2015) -
Clinicopathological characteristics and prognostic factors for intrahepatic cholangiocarcinoma: a population-based study
por: Tian-hua Yu, et al.
Publicado: (2021)