Assessing causal estimates of the association of obesity-related traits with coronary artery disease using a Mendelian randomization approach

Abstract Obesity-related traits have been associated with coronary artery disease (CAD) in observational studies, but these associations may be biased by confounding factors and reverse causation. In this study, we specifically conducted two-sample Mendelian randomization (MR) analyses to overcome t...

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Détails bibliographiques
Auteurs principaux: Xue Zhang, Wan-Qiang Lv, Bo Qiu, Li-Jun Zhang, Jian Qin, Feng-Juan Tang, Hai-Tao Wang, Hua-Jie Li, Ya-Rong Hao
Format: article
Langue:EN
Publié: Nature Portfolio 2018
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/f69c32ca22df442ead14f981d09085cc
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