Advancement of pharmacokinetic models of iohexol in patients aged 70 years or older with impaired kidney function

Advancement of pharmacokinetic models of iohexol in patients aged 70 years or older with impaired kidney function

Abstract Plasma clearance of iohexol is a pivotal metric to quantify glomerular filtration rate (GFR), but the optimal timing and frequency of plasma sampling remain to be assessed. In this study, we evaluated the impact of a Bayesian estimation procedure on iohexol clearance estimates, and we ident...

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Main Authors: Max Taubert, Elke Schaeffner, Peter Martus, Markus van der Giet, Uwe Fuhr, Amina Lösment, Natalie Ebert
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/f6a1f16dee5843c097c784d47edb7de6
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