Wnt2b attenuates HSCs activation and liver fibrosis through negative regulating TLR4 signaling

Abstract The Wingless-type MMTV integration site family member 2b (Wnt2b) has been found to be a principal mediator of liver development and regeneration. However, the significance of Wnt2b in the pathogenesis of fibrosis-related liver diseases remains undefined. Here, we report that Wnt2b was highl...

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Autores principales: Yi Yuan, Qiuju Han, Siyu Li, Zhigang Tian, Jian Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/f6a27d00a0784ffb91e909997028a95d
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