DHX9 helicase promotes R-loop formation in cells with impaired RNA splicing

Unresolved R-loops can represent a threat to genome stability. Here the authors reveal that DHX9 helicase can promote R-loop formation in the absence of splicing factors SFPQ and SF3B3.

Guardado en:

Detalles Bibliográficos
Autores principales:	Prasun Chakraborty, Jeffrey T. J. Huang, Kevin Hiom
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f6a6b01d7c104d91b1ab6b903aaebe70
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:f6a6b01d7c104d91b1ab6b903aaebe70
record_format	dspace
spelling	oai:doaj.org-article:f6a6b01d7c104d91b1ab6b903aaebe702021-12-02T17:31:47ZDHX9 helicase promotes R-loop formation in cells with impaired RNA splicing10.1038/s41467-018-06677-12041-1723https://doaj.org/article/f6a6b01d7c104d91b1ab6b903aaebe702018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06677-1https://doaj.org/toc/2041-1723Unresolved R-loops can represent a threat to genome stability. Here the authors reveal that DHX9 helicase can promote R-loop formation in the absence of splicing factors SFPQ and SF3B3.Prasun ChakrabortyJeffrey T. J. HuangKevin HiomNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Prasun Chakraborty Jeffrey T. J. Huang Kevin Hiom DHX9 helicase promotes R-loop formation in cells with impaired RNA splicing
description	Unresolved R-loops can represent a threat to genome stability. Here the authors reveal that DHX9 helicase can promote R-loop formation in the absence of splicing factors SFPQ and SF3B3.
format	article
author	Prasun Chakraborty Jeffrey T. J. Huang Kevin Hiom
author_facet	Prasun Chakraborty Jeffrey T. J. Huang Kevin Hiom
author_sort	Prasun Chakraborty
title	DHX9 helicase promotes R-loop formation in cells with impaired RNA splicing
title_short	DHX9 helicase promotes R-loop formation in cells with impaired RNA splicing
title_full	DHX9 helicase promotes R-loop formation in cells with impaired RNA splicing
title_fullStr	DHX9 helicase promotes R-loop formation in cells with impaired RNA splicing
title_full_unstemmed	DHX9 helicase promotes R-loop formation in cells with impaired RNA splicing
title_sort	dhx9 helicase promotes r-loop formation in cells with impaired rna splicing
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/f6a6b01d7c104d91b1ab6b903aaebe70
work_keys_str_mv	AT prasunchakraborty dhx9helicasepromotesrloopformationincellswithimpairedrnasplicing AT jeffreytjhuang dhx9helicasepromotesrloopformationincellswithimpairedrnasplicing AT kevinhiom dhx9helicasepromotesrloopformationincellswithimpairedrnasplicing
_version_	1718380529340907520

DHX9 helicase promotes R-loop formation in cells with impaired RNA splicing

Ejemplares similares