DHX9 helicase promotes R-loop formation in cells with impaired RNA splicing

Unresolved R-loops can represent a threat to genome stability. Here the authors reveal that DHX9 helicase can promote R-loop formation in the absence of splicing factors SFPQ and SF3B3.

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Bibliographic Details
Main Authors: Prasun Chakraborty, Jeffrey T. J. Huang, Kevin Hiom
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Q
Online Access:https://doaj.org/article/f6a6b01d7c104d91b1ab6b903aaebe70
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