Nanotechnology-based approaches in anticancer research

Nasimudeen R Jabir,1 Shams Tabrez,1 Ghulam Md Ashraf,2 Shazi Shakil,3 Ghazi A Damanhouri,4 Mohammad A Kamal11Metabolomics and Enzymology Unit, 2Proteomics and Structural Biology Unit, 3Enzoinformatics Unit, 4Hematology Research Unit, King Fahd Medical Research Center, King Abdulaziz University, Jedd...

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Autores principales: Jabir NR, Tabrez S, Ashraf GM, Shakil S, Damanhouri GA, Kamal MA
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Lenguaje:EN
Publicado: Dove Medical Press 2012
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Acceso en línea:https://doaj.org/article/f6b384a5045149feb81fd86858c03b4a
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spelling oai:doaj.org-article:f6b384a5045149feb81fd86858c03b4a2021-12-02T04:46:24ZNanotechnology-based approaches in anticancer research1176-91141178-2013https://doaj.org/article/f6b384a5045149feb81fd86858c03b4a2012-08-01T00:00:00Zhttp://www.dovepress.com/nanotechnology-based-approaches-in-anticancer-research-a10647https://doaj.org/toc/1176-9114https://doaj.org/toc/1178-2013Nasimudeen R Jabir,1 Shams Tabrez,1 Ghulam Md Ashraf,2 Shazi Shakil,3 Ghazi A Damanhouri,4 Mohammad A Kamal11Metabolomics and Enzymology Unit, 2Proteomics and Structural Biology Unit, 3Enzoinformatics Unit, 4Hematology Research Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi ArabiaAbstract: Cancer is a highly complex disease to understand, because it entails multiple cellular physiological systems. The most common cancer treatments are restricted to chemotherapy, radiation and surgery. Moreover, the early recognition and treatment of cancer remains a technological bottleneck. There is an urgent need to develop new and innovative technologies that could help to delineate tumor margins, identify residual tumor cells and micrometastases, and determine whether a tumor has been completely removed or not. Nanotechnology has witnessed significant progress in the past few decades, and its effect is widespread nowadays in every field. Nanoparticles can be modified in numerous ways to prolong circulation, enhance drug localization, increase drug efficacy, and potentially decrease chances of multidrug resistance by the use of nanotechnology. Recently, research in the field of cancer nanotechnology has made remarkable advances. The present review summarizes the application of various nanotechnology-based approaches towards the diagnostics and therapeutics of cancer.Keywords: cancer, diagnosis, drug delivery, nanoparticle, nanotechnology, treatmentJabir NRTabrez SAshraf GMShakil SDamanhouri GAKamal MADove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2012, Iss default, Pp 4391-4408 (2012)
institution DOAJ
collection DOAJ
language EN
topic Medicine (General)
R5-920
spellingShingle Medicine (General)
R5-920
Jabir NR
Tabrez S
Ashraf GM
Shakil S
Damanhouri GA
Kamal MA
Nanotechnology-based approaches in anticancer research
description Nasimudeen R Jabir,1 Shams Tabrez,1 Ghulam Md Ashraf,2 Shazi Shakil,3 Ghazi A Damanhouri,4 Mohammad A Kamal11Metabolomics and Enzymology Unit, 2Proteomics and Structural Biology Unit, 3Enzoinformatics Unit, 4Hematology Research Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi ArabiaAbstract: Cancer is a highly complex disease to understand, because it entails multiple cellular physiological systems. The most common cancer treatments are restricted to chemotherapy, radiation and surgery. Moreover, the early recognition and treatment of cancer remains a technological bottleneck. There is an urgent need to develop new and innovative technologies that could help to delineate tumor margins, identify residual tumor cells and micrometastases, and determine whether a tumor has been completely removed or not. Nanotechnology has witnessed significant progress in the past few decades, and its effect is widespread nowadays in every field. Nanoparticles can be modified in numerous ways to prolong circulation, enhance drug localization, increase drug efficacy, and potentially decrease chances of multidrug resistance by the use of nanotechnology. Recently, research in the field of cancer nanotechnology has made remarkable advances. The present review summarizes the application of various nanotechnology-based approaches towards the diagnostics and therapeutics of cancer.Keywords: cancer, diagnosis, drug delivery, nanoparticle, nanotechnology, treatment
format article
author Jabir NR
Tabrez S
Ashraf GM
Shakil S
Damanhouri GA
Kamal MA
author_facet Jabir NR
Tabrez S
Ashraf GM
Shakil S
Damanhouri GA
Kamal MA
author_sort Jabir NR
title Nanotechnology-based approaches in anticancer research
title_short Nanotechnology-based approaches in anticancer research
title_full Nanotechnology-based approaches in anticancer research
title_fullStr Nanotechnology-based approaches in anticancer research
title_full_unstemmed Nanotechnology-based approaches in anticancer research
title_sort nanotechnology-based approaches in anticancer research
publisher Dove Medical Press
publishDate 2012
url https://doaj.org/article/f6b384a5045149feb81fd86858c03b4a
work_keys_str_mv AT jabirnr nanotechnologybasedapproachesinanticancerresearch
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AT ashrafgm nanotechnologybasedapproachesinanticancerresearch
AT shakils nanotechnologybasedapproachesinanticancerresearch
AT damanhouriga nanotechnologybasedapproachesinanticancerresearch
AT kamalma nanotechnologybasedapproachesinanticancerresearch
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