Semiconducting polymer nano-PROTACs for activatable photo-immunometabolic cancer therapy

Proteolysis targeting chimeras (PROTACs) is an effective alternative to modulate protein homeostasis but can lead to uncontrollable protein degradation and off-target side effects. Here, the authors developed semiconducting polymer nano-PROTACs with phototherapeutic and activatable protein degradati...

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Auteurs principaux: Chi Zhang, Ziling Zeng, Dong Cui, Shasha He, Yuyan Jiang, Jingchao Li, Jiaguo Huang, Kanyi Pu
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/f6b826023896477c9ccf92b806a2fbfb
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