Dynamic remodelling of the human host cell proteome and phosphoproteome upon enterovirus infection

Here, Giansanti et al. perform a system-wide and time-resolved characterization of the changes in the host cell proteome and phosphoproteome of cells infected with the enterovirus coxsackievirus B3 during a full round of replication and identify mTORC1 signalling as a major regulation network during...

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Autores principales: Piero Giansanti, Jeroen R. P. M. Strating, Kyra A. Y. Defourny, Ieva Cesonyte, Alexia M. S. Bottino, Harm Post, Ekaterina G. Viktorova, Vien Quang Tri Ho, Martijn A. Langereis, George A. Belov, Esther N. M. Nolte-‘t Hoen, Albert J. R. Heck, Frank J. M. van Kuppeveld
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/f6c324bdfe0e47ba949b2bdd1df1f91a
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spelling oai:doaj.org-article:f6c324bdfe0e47ba949b2bdd1df1f91a2021-12-02T15:09:18ZDynamic remodelling of the human host cell proteome and phosphoproteome upon enterovirus infection10.1038/s41467-020-18168-32041-1723https://doaj.org/article/f6c324bdfe0e47ba949b2bdd1df1f91a2020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18168-3https://doaj.org/toc/2041-1723Here, Giansanti et al. perform a system-wide and time-resolved characterization of the changes in the host cell proteome and phosphoproteome of cells infected with the enterovirus coxsackievirus B3 during a full round of replication and identify mTORC1 signalling as a major regulation network during virus infection.Piero GiansantiJeroen R. P. M. StratingKyra A. Y. DefournyIeva CesonyteAlexia M. S. BottinoHarm PostEkaterina G. ViktorovaVien Quang Tri HoMartijn A. LangereisGeorge A. BelovEsther N. M. Nolte-‘t HoenAlbert J. R. HeckFrank J. M. van KuppeveldNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Piero Giansanti
Jeroen R. P. M. Strating
Kyra A. Y. Defourny
Ieva Cesonyte
Alexia M. S. Bottino
Harm Post
Ekaterina G. Viktorova
Vien Quang Tri Ho
Martijn A. Langereis
George A. Belov
Esther N. M. Nolte-‘t Hoen
Albert J. R. Heck
Frank J. M. van Kuppeveld
Dynamic remodelling of the human host cell proteome and phosphoproteome upon enterovirus infection
description Here, Giansanti et al. perform a system-wide and time-resolved characterization of the changes in the host cell proteome and phosphoproteome of cells infected with the enterovirus coxsackievirus B3 during a full round of replication and identify mTORC1 signalling as a major regulation network during virus infection.
format article
author Piero Giansanti
Jeroen R. P. M. Strating
Kyra A. Y. Defourny
Ieva Cesonyte
Alexia M. S. Bottino
Harm Post
Ekaterina G. Viktorova
Vien Quang Tri Ho
Martijn A. Langereis
George A. Belov
Esther N. M. Nolte-‘t Hoen
Albert J. R. Heck
Frank J. M. van Kuppeveld
author_facet Piero Giansanti
Jeroen R. P. M. Strating
Kyra A. Y. Defourny
Ieva Cesonyte
Alexia M. S. Bottino
Harm Post
Ekaterina G. Viktorova
Vien Quang Tri Ho
Martijn A. Langereis
George A. Belov
Esther N. M. Nolte-‘t Hoen
Albert J. R. Heck
Frank J. M. van Kuppeveld
author_sort Piero Giansanti
title Dynamic remodelling of the human host cell proteome and phosphoproteome upon enterovirus infection
title_short Dynamic remodelling of the human host cell proteome and phosphoproteome upon enterovirus infection
title_full Dynamic remodelling of the human host cell proteome and phosphoproteome upon enterovirus infection
title_fullStr Dynamic remodelling of the human host cell proteome and phosphoproteome upon enterovirus infection
title_full_unstemmed Dynamic remodelling of the human host cell proteome and phosphoproteome upon enterovirus infection
title_sort dynamic remodelling of the human host cell proteome and phosphoproteome upon enterovirus infection
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/f6c324bdfe0e47ba949b2bdd1df1f91a
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