Genomic characterization and outcome evaluation of kinome fusions in lung cancer revealed novel druggable fusions
Abstract Kinase fusions represent an important type of somatic alterations that promote oncogenesis and serve as diagnostic markers in lung cancer. We aimed to identify the landscape of clinically relevant kinase fusions in Chinese lung cancer and to explore rare kinase rearrangements; thus, providi...
Guardado en:
Autores principales: | Binghao Li, Hao Qu, Jing Zhang, Weibo Pan, Meng Liu, Xiaobo Yan, Xin Huang, Xuexin He, Dong Lin, Sisi Liu, Ruting Guan, Yong Wu, Qiuxiang Ou, Hua Bao, Youbin Xu, Xue Wu, Yang Shao, Nong Lin |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/f6cba414f712492aaf01108493a887d1 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Proteogenomics analysis unveils a TFG-RET gene fusion and druggable targets in papillary thyroid carcinomas
por: Aswini Krishnan, et al.
Publicado: (2020) -
Integrated omics in Drosophila uncover a circadian kinome
por: Chenwei Wang, et al.
Publicado: (2020) - Information fusion
-
KRAS mutation: from undruggable to druggable in cancer
por: Lamei Huang, et al.
Publicado: (2021) -
Image perception hash and structural similarity fusion model for parking lot status recognition
por: Zhi-Fa Yang, et al.
Publicado: (2019)