Impact of Natural Blind Spot Location on Perimetry

Abstract We study the spatial distribution of natural blind spot location (NBSL) and its impact on perimetry. Pattern deviation (PD) values of 11,449 reliable visual fields (VFs) that are defined as clinically unaffected based on summary indices were extracted from 11,449 glaucoma patients. We model...

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Autores principales:	Mengyu Wang, Lucy Q. Shen, Michael V. Boland, Sarah R. Wellik, Carlos Gustavo De Moraes, Jonathan S. Myers, Peter J. Bex, Tobias Elze
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/f6d610b24ba844cfb2f0df8dabd16b8d
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spelling	oai:doaj.org-article:f6d610b24ba844cfb2f0df8dabd16b8d2021-12-02T15:05:00ZImpact of Natural Blind Spot Location on Perimetry10.1038/s41598-017-06580-72045-2322https://doaj.org/article/f6d610b24ba844cfb2f0df8dabd16b8d2017-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-06580-7https://doaj.org/toc/2045-2322Abstract We study the spatial distribution of natural blind spot location (NBSL) and its impact on perimetry. Pattern deviation (PD) values of 11,449 reliable visual fields (VFs) that are defined as clinically unaffected based on summary indices were extracted from 11,449 glaucoma patients. We modeled NBSL distribution using a two-dimensional non-linear regression approach and correlated NBSL with spherical equivalent (SE). Additionally, we compared PD values of groups with longer and shorter distances than median, and larger and smaller angles than median between NBSL and fixation. Mean and standard deviation of horizontal and vertical NBSL were 14.33° ± 1.37° and −2.06° ± 1.27°, respectively. SE decreased with increasing NBSL (correlation: r = −0.14, p < 0.001). For NBSL distances longer than median distance (14.32°), average PD values decreased in the upper central (average difference for significant points (ADSP): −0.18 dB) and increased in the lower nasal VF region (ADSP: 0.14 dB). For angles in the direction of upper hemifield relative to the median angle (−8.13°), PD values decreased in lower nasal (ADSP: −0.11 dB) and increased in upper temporal VF areas (ADSP: 0.19 dB). In conclusion, we demonstrate that NBSL has a systematic effect on the spatial distribution of VF sensitivity.Mengyu WangLucy Q. ShenMichael V. BolandSarah R. WellikCarlos Gustavo De MoraesJonathan S. MyersPeter J. BexTobias ElzeNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Mengyu Wang Lucy Q. Shen Michael V. Boland Sarah R. Wellik Carlos Gustavo De Moraes Jonathan S. Myers Peter J. Bex Tobias Elze Impact of Natural Blind Spot Location on Perimetry
description	Abstract We study the spatial distribution of natural blind spot location (NBSL) and its impact on perimetry. Pattern deviation (PD) values of 11,449 reliable visual fields (VFs) that are defined as clinically unaffected based on summary indices were extracted from 11,449 glaucoma patients. We modeled NBSL distribution using a two-dimensional non-linear regression approach and correlated NBSL with spherical equivalent (SE). Additionally, we compared PD values of groups with longer and shorter distances than median, and larger and smaller angles than median between NBSL and fixation. Mean and standard deviation of horizontal and vertical NBSL were 14.33° ± 1.37° and −2.06° ± 1.27°, respectively. SE decreased with increasing NBSL (correlation: r = −0.14, p < 0.001). For NBSL distances longer than median distance (14.32°), average PD values decreased in the upper central (average difference for significant points (ADSP): −0.18 dB) and increased in the lower nasal VF region (ADSP: 0.14 dB). For angles in the direction of upper hemifield relative to the median angle (−8.13°), PD values decreased in lower nasal (ADSP: −0.11 dB) and increased in upper temporal VF areas (ADSP: 0.19 dB). In conclusion, we demonstrate that NBSL has a systematic effect on the spatial distribution of VF sensitivity.
format	article
author	Mengyu Wang Lucy Q. Shen Michael V. Boland Sarah R. Wellik Carlos Gustavo De Moraes Jonathan S. Myers Peter J. Bex Tobias Elze
author_facet	Mengyu Wang Lucy Q. Shen Michael V. Boland Sarah R. Wellik Carlos Gustavo De Moraes Jonathan S. Myers Peter J. Bex Tobias Elze
author_sort	Mengyu Wang
title	Impact of Natural Blind Spot Location on Perimetry
title_short	Impact of Natural Blind Spot Location on Perimetry
title_full	Impact of Natural Blind Spot Location on Perimetry
title_fullStr	Impact of Natural Blind Spot Location on Perimetry
title_full_unstemmed	Impact of Natural Blind Spot Location on Perimetry
title_sort	impact of natural blind spot location on perimetry
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/f6d610b24ba844cfb2f0df8dabd16b8d
work_keys_str_mv	AT mengyuwang impactofnaturalblindspotlocationonperimetry AT lucyqshen impactofnaturalblindspotlocationonperimetry AT michaelvboland impactofnaturalblindspotlocationonperimetry AT sarahrwellik impactofnaturalblindspotlocationonperimetry AT carlosgustavodemoraes impactofnaturalblindspotlocationonperimetry AT jonathansmyers impactofnaturalblindspotlocationonperimetry AT peterjbex impactofnaturalblindspotlocationonperimetry AT tobiaselze impactofnaturalblindspotlocationonperimetry
_version_	1718388992832962560

Impact of Natural Blind Spot Location on Perimetry

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