Long-lasting antidepressant action of ketamine, but not glycogen synthase kinase-3 inhibitor SB216763, in the chronic mild stress model of mice.
<h4>Background</h4>Clinical studies demonstrate that the N-methyl-D-aspartate (NMDA) receptor antagonist, ketamine, induces rapid antidepressant effects in patients with refractive major depressive disorder and bipolar depression. This rapid onset of action makes ketamine a highly attrac...
Saved in:
Main Authors: | Xian-Cang Ma, Yong-Hui Dang, Min Jia, Rui Ma, Fen Wang, Jin Wu, Cheng-Ge Gao, Kenji Hashimoto |
---|---|
Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2013
|
Subjects: | |
Online Access: | https://doaj.org/article/f6d992536b5f434f962039d9df81ab91 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
In vivo regulation of glycogen synthase kinase 3β activity in neurons and brains
by: Ambika Krishnankutty, et al.
Published: (2017) -
Immunoregulation and antidepressant effect of ketamine
by: Zhang Nan, et al.
Published: (2021) -
Glycogen synthase kinase 3 controls migration of the neural crest lineage in mouse and Xenopus
by: Sandra G. Gonzalez Malagon, et al.
Published: (2018) -
The role of dissociation in ketamine’s antidepressant effects
by: Elizabeth D. Ballard, et al.
Published: (2020) -
Regulation of persistent sodium currents by glycogen synthase kinase 3 encodes daily rhythms of neuronal excitability
by: Jodi R. Paul, et al.
Published: (2016)