An Oxidative Stress-Related Gene Pair (CCNB1/PKD1), Competitive Endogenous RNAs, and Immune-Infiltration Patterns Potentially Regulate Intervertebral Disc Degeneration Development

An Oxidative Stress-Related Gene Pair (CCNB1/PKD1), Competitive Endogenous RNAs, and Immune-Infiltration Patterns Potentially Regulate Intervertebral Disc Degeneration Development

Oxidative stress (OS) irreversibly affects the pathogenesis of intervertebral disc degeneration (IDD). Certain non-coding RNAs act as competitive endogenous RNAs (ceRNAs) that regulate IDD progression. Analyzing the signatures of oxidative stress-related gene (OSRG) pairs and regulatory ceRNA mechan...

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Bibliographic Details
Main Authors: Shuai Cao, Hao Liu, Jiaxin Fan, Kai Yang, Baohui Yang, Jie Wang, Jie Li, Liesu Meng, Haopeng Li
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
intervertebral disc degeneration
oxidative stress
gene pair
immune infiltration
competitive endogenous RNA
differential expression
Immunologic diseases. Allergy
RC581-607
Online Access:https://doaj.org/article/f6e0ad8ce8ad48c396aa7306aadd0d91
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