Cloud-Based Software Architecture for Fully Automated Point-of-Care Molecular Diagnostic Device

This paper proposes a cloud-based software architecture for fully automated point-of-care molecular diagnostic devices. The target system operates a cartridge consisting of an extraction body for DNA extraction and a PCR chip for amplification and fluorescence detection. To facilitate control and mo...

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Autores principales:	Byeong-Heon Kil, Ji-Seong Park, Mun-Ho Ryu, Chan-Young Park, Yu-Seop Kim, Jong-Dae Kim
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	fully automated molecular diagnostic system point-of-care cloud-based web-based user interface Chemical technology TP1-1185
Acceso en línea:	https://doaj.org/article/f6f18f9abf5d4089bde5fc21c7345ab1
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id	oai:doaj.org-article:f6f18f9abf5d4089bde5fc21c7345ab1
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spelling	oai:doaj.org-article:f6f18f9abf5d4089bde5fc21c7345ab12021-11-11T19:01:35ZCloud-Based Software Architecture for Fully Automated Point-of-Care Molecular Diagnostic Device10.3390/s212169801424-8220https://doaj.org/article/f6f18f9abf5d4089bde5fc21c7345ab12021-10-01T00:00:00Zhttps://www.mdpi.com/1424-8220/21/21/6980https://doaj.org/toc/1424-8220This paper proposes a cloud-based software architecture for fully automated point-of-care molecular diagnostic devices. The target system operates a cartridge consisting of an extraction body for DNA extraction and a PCR chip for amplification and fluorescence detection. To facilitate control and monitoring via the cloud, a socket server was employed for fundamental molecular diagnostic functions such as DNA extraction, amplification, and fluorescence detection. The user interface for experimental control and monitoring was constructed with the RESTful application programming interface, allowing access from the terminal device, edge, and cloud. Furthermore, it can also be accessed through any web-based user interface on smart computing devices such as smart phones or tablets. An emulator with the proposed software architecture was fabricated to validate successful operation.Byeong-Heon KilJi-Seong ParkMun-Ho RyuChan-Young ParkYu-Seop KimJong-Dae KimMDPI AGarticlefully automated molecular diagnostic systempoint-of-carecloud-basedweb-based user interfaceChemical technologyTP1-1185ENSensors, Vol 21, Iss 6980, p 6980 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	fully automated molecular diagnostic system point-of-care cloud-based web-based user interface Chemical technology TP1-1185
spellingShingle	fully automated molecular diagnostic system point-of-care cloud-based web-based user interface Chemical technology TP1-1185 Byeong-Heon Kil Ji-Seong Park Mun-Ho Ryu Chan-Young Park Yu-Seop Kim Jong-Dae Kim Cloud-Based Software Architecture for Fully Automated Point-of-Care Molecular Diagnostic Device
description	This paper proposes a cloud-based software architecture for fully automated point-of-care molecular diagnostic devices. The target system operates a cartridge consisting of an extraction body for DNA extraction and a PCR chip for amplification and fluorescence detection. To facilitate control and monitoring via the cloud, a socket server was employed for fundamental molecular diagnostic functions such as DNA extraction, amplification, and fluorescence detection. The user interface for experimental control and monitoring was constructed with the RESTful application programming interface, allowing access from the terminal device, edge, and cloud. Furthermore, it can also be accessed through any web-based user interface on smart computing devices such as smart phones or tablets. An emulator with the proposed software architecture was fabricated to validate successful operation.
format	article
author	Byeong-Heon Kil Ji-Seong Park Mun-Ho Ryu Chan-Young Park Yu-Seop Kim Jong-Dae Kim
author_facet	Byeong-Heon Kil Ji-Seong Park Mun-Ho Ryu Chan-Young Park Yu-Seop Kim Jong-Dae Kim
author_sort	Byeong-Heon Kil
title	Cloud-Based Software Architecture for Fully Automated Point-of-Care Molecular Diagnostic Device
title_short	Cloud-Based Software Architecture for Fully Automated Point-of-Care Molecular Diagnostic Device
title_full	Cloud-Based Software Architecture for Fully Automated Point-of-Care Molecular Diagnostic Device
title_fullStr	Cloud-Based Software Architecture for Fully Automated Point-of-Care Molecular Diagnostic Device
title_full_unstemmed	Cloud-Based Software Architecture for Fully Automated Point-of-Care Molecular Diagnostic Device
title_sort	cloud-based software architecture for fully automated point-of-care molecular diagnostic device
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/f6f18f9abf5d4089bde5fc21c7345ab1
work_keys_str_mv	AT byeongheonkil cloudbasedsoftwarearchitectureforfullyautomatedpointofcaremoleculardiagnosticdevice AT jiseongpark cloudbasedsoftwarearchitectureforfullyautomatedpointofcaremoleculardiagnosticdevice AT munhoryu cloudbasedsoftwarearchitectureforfullyautomatedpointofcaremoleculardiagnosticdevice AT chanyoungpark cloudbasedsoftwarearchitectureforfullyautomatedpointofcaremoleculardiagnosticdevice AT yuseopkim cloudbasedsoftwarearchitectureforfullyautomatedpointofcaremoleculardiagnosticdevice AT jongdaekim cloudbasedsoftwarearchitectureforfullyautomatedpointofcaremoleculardiagnosticdevice
_version_	1718431681195540480

Cloud-Based Software Architecture for Fully Automated Point-of-Care Molecular Diagnostic Device

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