Selective recruitment of different Ca2+-dependent transcription factors by STIM1-Orai1 channel clusters

Endoplasmic reticulum Ca2+ sensing STIM proteins and plasma membrane Orai1 channels together regulate Ca2+ influx in eukaryotic cells. Here authors show that two Ca2+-dependent transcription factors, NFAT1 and c-fos, have different requirements for the number of STIM1-Orai1 clusters and on the Ca2+...

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Autores principales:	Yu-Ping Lin, Daniel Bakowski, Gary R. Mirams, Anant B. Parekh
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f7012bdab71a4863ad46f80012f557ad
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spelling	oai:doaj.org-article:f7012bdab71a4863ad46f80012f557ad2021-12-02T16:50:58ZSelective recruitment of different Ca2+-dependent transcription factors by STIM1-Orai1 channel clusters10.1038/s41467-019-10329-32041-1723https://doaj.org/article/f7012bdab71a4863ad46f80012f557ad2019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10329-3https://doaj.org/toc/2041-1723Endoplasmic reticulum Ca2+ sensing STIM proteins and plasma membrane Orai1 channels together regulate Ca2+ influx in eukaryotic cells. Here authors show that two Ca2+-dependent transcription factors, NFAT1 and c-fos, have different requirements for the number of STIM1-Orai1 clusters and on the Ca2+ flux through the clusters.Yu-Ping LinDaniel BakowskiGary R. MiramsAnant B. ParekhNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yu-Ping Lin Daniel Bakowski Gary R. Mirams Anant B. Parekh Selective recruitment of different Ca2+-dependent transcription factors by STIM1-Orai1 channel clusters
description	Endoplasmic reticulum Ca2+ sensing STIM proteins and plasma membrane Orai1 channels together regulate Ca2+ influx in eukaryotic cells. Here authors show that two Ca2+-dependent transcription factors, NFAT1 and c-fos, have different requirements for the number of STIM1-Orai1 clusters and on the Ca2+ flux through the clusters.
format	article
author	Yu-Ping Lin Daniel Bakowski Gary R. Mirams Anant B. Parekh
author_facet	Yu-Ping Lin Daniel Bakowski Gary R. Mirams Anant B. Parekh
author_sort	Yu-Ping Lin
title	Selective recruitment of different Ca2+-dependent transcription factors by STIM1-Orai1 channel clusters
title_short	Selective recruitment of different Ca2+-dependent transcription factors by STIM1-Orai1 channel clusters
title_full	Selective recruitment of different Ca2+-dependent transcription factors by STIM1-Orai1 channel clusters
title_fullStr	Selective recruitment of different Ca2+-dependent transcription factors by STIM1-Orai1 channel clusters
title_full_unstemmed	Selective recruitment of different Ca2+-dependent transcription factors by STIM1-Orai1 channel clusters
title_sort	selective recruitment of different ca2+-dependent transcription factors by stim1-orai1 channel clusters
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/f7012bdab71a4863ad46f80012f557ad
work_keys_str_mv	AT yupinglin selectiverecruitmentofdifferentca2dependenttranscriptionfactorsbystim1orai1channelclusters AT danielbakowski selectiverecruitmentofdifferentca2dependenttranscriptionfactorsbystim1orai1channelclusters AT garyrmirams selectiverecruitmentofdifferentca2dependenttranscriptionfactorsbystim1orai1channelclusters AT anantbparekh selectiverecruitmentofdifferentca2dependenttranscriptionfactorsbystim1orai1channelclusters
_version_	1718383015792476160

Selective recruitment of different Ca2+-dependent transcription factors by STIM1-Orai1 channel clusters

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