Selective recruitment of different Ca2+-dependent transcription factors by STIM1-Orai1 channel clusters

Endoplasmic reticulum Ca2+ sensing STIM proteins and plasma membrane Orai1 channels together regulate Ca2+ influx in eukaryotic cells. Here authors show that two Ca2+-dependent transcription factors, NFAT1 and c-fos, have different requirements for the number of STIM1-Orai1 clusters and on the Ca2+...

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Autores principales: Yu-Ping Lin, Daniel Bakowski, Gary R. Mirams, Anant B. Parekh
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/f7012bdab71a4863ad46f80012f557ad
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