Two mechanisms drive pronuclear migration in mouse zygotes

Two mechanisms drive pronuclear migration in mouse zygotes

In a newly fertilized egg, maternal and paternal chromosomes are enclosed in two separate pronuclei but the mechanisms in mammals for pronuclear movement are unclear. Here, the authors report that both F-actin and microtubule polymerization act in concern to drive inward movement of pronuclei toward...

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Autores principales: Kathleen Scheffler, Julia Uraji, Ida Jentoft, Tommaso Cavazza, Eike Mönnich, Binyam Mogessie, Melina Schuh
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/f7141fa023074c7ba56342406e25c610
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spelling oai:doaj.org-article:f7141fa023074c7ba56342406e25c6102021-12-02T14:06:28ZTwo mechanisms drive pronuclear migration in mouse zygotes10.1038/s41467-021-21020-x2041-1723https://doaj.org/article/f7141fa023074c7ba56342406e25c6102021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21020-xhttps://doaj.org/toc/2041-1723In a newly fertilized egg, maternal and paternal chromosomes are enclosed in two separate pronuclei but the mechanisms in mammals for pronuclear movement are unclear. Here, the authors report that both F-actin and microtubule polymerization act in concern to drive inward movement of pronuclei towards the cell centre.Kathleen SchefflerJulia UrajiIda JentoftTommaso CavazzaEike MönnichBinyam MogessieMelina SchuhNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Kathleen Scheffler
Julia Uraji
Ida Jentoft
Tommaso Cavazza
Eike Mönnich
Binyam Mogessie
Melina Schuh
Two mechanisms drive pronuclear migration in mouse zygotes
description In a newly fertilized egg, maternal and paternal chromosomes are enclosed in two separate pronuclei but the mechanisms in mammals for pronuclear movement are unclear. Here, the authors report that both F-actin and microtubule polymerization act in concern to drive inward movement of pronuclei towards the cell centre.
format article
author Kathleen Scheffler
Julia Uraji
Ida Jentoft
Tommaso Cavazza
Eike Mönnich
Binyam Mogessie
Melina Schuh
author_facet Kathleen Scheffler
Julia Uraji
Ida Jentoft
Tommaso Cavazza
Eike Mönnich
Binyam Mogessie
Melina Schuh
author_sort Kathleen Scheffler
title Two mechanisms drive pronuclear migration in mouse zygotes
title_short Two mechanisms drive pronuclear migration in mouse zygotes
title_full Two mechanisms drive pronuclear migration in mouse zygotes
title_fullStr Two mechanisms drive pronuclear migration in mouse zygotes
title_full_unstemmed Two mechanisms drive pronuclear migration in mouse zygotes
title_sort two mechanisms drive pronuclear migration in mouse zygotes
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/f7141fa023074c7ba56342406e25c610
work_keys_str_mv AT kathleenscheffler twomechanismsdrivepronuclearmigrationinmousezygotes
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AT tommasocavazza twomechanismsdrivepronuclearmigrationinmousezygotes
AT eikemonnich twomechanismsdrivepronuclearmigrationinmousezygotes
AT binyammogessie twomechanismsdrivepronuclearmigrationinmousezygotes
AT melinaschuh twomechanismsdrivepronuclearmigrationinmousezygotes
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