A nanoscale metal organic frameworks-based vaccine synergises with PD-1 blockade to potentiate anti-tumour immunity

Nanoparticle-based strategies have been proposed to enhance the benefit of cancer immunotherapy. Here the authors show that a cancer vaccine based on metal organic frameworks-gated mesoporous silica nanoparticles for antigen and immune potentiators delivery boosts the therapeutic efficacy of low-dos...

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Bibliographic Details
Main Authors: Xia Li, Xiupeng Wang, Atsuo Ito, Noriko M. Tsuji
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
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Online Access:https://doaj.org/article/f71839f40174497792c5136e0d1bd3f5
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