Molecular profiling of driver events in metastatic uveal melanoma

The genetics of uveal melanoma has mainly been studied in primary tumours. In this study, the authors perform whole genome sequencing as well as immune cell profiling of biopsy samples obtained from metastatic uveal melanoma patients, providing an updated genomic landscape of these advanced lesions.

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Autores principales:	Joakim Karlsson, Lisa M. Nilsson, Suman Mitra, Samuel Alsén, Ganesh Vilas Shelke, Vasu R. Sah, Elin M. V. Forsberg, Ulrika Stierner, Charlotta All-Eriksson, Berglind Einarsdottir, Henrik Jespersen, Lars Ny, Per Lindnér, Erik Larsson, Roger Olofsson Bagge, Jonas A. Nilsson
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f71cb61f5c524059bea90c9e29676365
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spelling	oai:doaj.org-article:f71cb61f5c524059bea90c9e296763652021-12-02T16:50:00ZMolecular profiling of driver events in metastatic uveal melanoma10.1038/s41467-020-15606-02041-1723https://doaj.org/article/f71cb61f5c524059bea90c9e296763652020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15606-0https://doaj.org/toc/2041-1723The genetics of uveal melanoma has mainly been studied in primary tumours. In this study, the authors perform whole genome sequencing as well as immune cell profiling of biopsy samples obtained from metastatic uveal melanoma patients, providing an updated genomic landscape of these advanced lesions.Joakim KarlssonLisa M. NilssonSuman MitraSamuel AlsénGanesh Vilas ShelkeVasu R. SahElin M. V. ForsbergUlrika StiernerCharlotta All-ErikssonBerglind EinarsdottirHenrik JespersenLars NyPer LindnérErik LarssonRoger Olofsson BaggeJonas A. NilssonNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Joakim Karlsson Lisa M. Nilsson Suman Mitra Samuel Alsén Ganesh Vilas Shelke Vasu R. Sah Elin M. V. Forsberg Ulrika Stierner Charlotta All-Eriksson Berglind Einarsdottir Henrik Jespersen Lars Ny Per Lindnér Erik Larsson Roger Olofsson Bagge Jonas A. Nilsson Molecular profiling of driver events in metastatic uveal melanoma
description	The genetics of uveal melanoma has mainly been studied in primary tumours. In this study, the authors perform whole genome sequencing as well as immune cell profiling of biopsy samples obtained from metastatic uveal melanoma patients, providing an updated genomic landscape of these advanced lesions.
format	article
author	Joakim Karlsson Lisa M. Nilsson Suman Mitra Samuel Alsén Ganesh Vilas Shelke Vasu R. Sah Elin M. V. Forsberg Ulrika Stierner Charlotta All-Eriksson Berglind Einarsdottir Henrik Jespersen Lars Ny Per Lindnér Erik Larsson Roger Olofsson Bagge Jonas A. Nilsson
author_facet	Joakim Karlsson Lisa M. Nilsson Suman Mitra Samuel Alsén Ganesh Vilas Shelke Vasu R. Sah Elin M. V. Forsberg Ulrika Stierner Charlotta All-Eriksson Berglind Einarsdottir Henrik Jespersen Lars Ny Per Lindnér Erik Larsson Roger Olofsson Bagge Jonas A. Nilsson
author_sort	Joakim Karlsson
title	Molecular profiling of driver events in metastatic uveal melanoma
title_short	Molecular profiling of driver events in metastatic uveal melanoma
title_full	Molecular profiling of driver events in metastatic uveal melanoma
title_fullStr	Molecular profiling of driver events in metastatic uveal melanoma
title_full_unstemmed	Molecular profiling of driver events in metastatic uveal melanoma
title_sort	molecular profiling of driver events in metastatic uveal melanoma
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/f71cb61f5c524059bea90c9e29676365
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Molecular profiling of driver events in metastatic uveal melanoma

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