CryoEM structure of the outer membrane secretin channel pIV from the f1 filamentous bacteriophage

New virions of Ff bacteriophages are extruded from the host cell via the channel built from phage protein pIV, homologous to bacterial secretins. Here, the authors report the structure of this channel from the f1 filamentous bacteriophage and propose its use as an adjuvant to increase the uptake and...

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Autores principales:	Rebecca Conners, Mathew McLaren, Urszula Łapińska, Kelly Sanders, M. Rhia L. Stone, Mark A. T. Blaskovich, Stefano Pagliara, Bertram Daum, Jasna Rakonjac, Vicki A. M. Gold
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f71d9956f4a9496997c3360054dba2c1
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spelling	oai:doaj.org-article:f71d9956f4a9496997c3360054dba2c12021-11-08T11:07:41ZCryoEM structure of the outer membrane secretin channel pIV from the f1 filamentous bacteriophage10.1038/s41467-021-26610-32041-1723https://doaj.org/article/f71d9956f4a9496997c3360054dba2c12021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26610-3https://doaj.org/toc/2041-1723New virions of Ff bacteriophages are extruded from the host cell via the channel built from phage protein pIV, homologous to bacterial secretins. Here, the authors report the structure of this channel from the f1 filamentous bacteriophage and propose its use as an adjuvant to increase the uptake and efficacy of antibiotics.Rebecca ConnersMathew McLarenUrszula ŁapińskaKelly SandersM. Rhia L. StoneMark A. T. BlaskovichStefano PagliaraBertram DaumJasna RakonjacVicki A. M. GoldNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Rebecca Conners Mathew McLaren Urszula Łapińska Kelly Sanders M. Rhia L. Stone Mark A. T. Blaskovich Stefano Pagliara Bertram Daum Jasna Rakonjac Vicki A. M. Gold CryoEM structure of the outer membrane secretin channel pIV from the f1 filamentous bacteriophage
description	New virions of Ff bacteriophages are extruded from the host cell via the channel built from phage protein pIV, homologous to bacterial secretins. Here, the authors report the structure of this channel from the f1 filamentous bacteriophage and propose its use as an adjuvant to increase the uptake and efficacy of antibiotics.
format	article
author	Rebecca Conners Mathew McLaren Urszula Łapińska Kelly Sanders M. Rhia L. Stone Mark A. T. Blaskovich Stefano Pagliara Bertram Daum Jasna Rakonjac Vicki A. M. Gold
author_facet	Rebecca Conners Mathew McLaren Urszula Łapińska Kelly Sanders M. Rhia L. Stone Mark A. T. Blaskovich Stefano Pagliara Bertram Daum Jasna Rakonjac Vicki A. M. Gold
author_sort	Rebecca Conners
title	CryoEM structure of the outer membrane secretin channel pIV from the f1 filamentous bacteriophage
title_short	CryoEM structure of the outer membrane secretin channel pIV from the f1 filamentous bacteriophage
title_full	CryoEM structure of the outer membrane secretin channel pIV from the f1 filamentous bacteriophage
title_fullStr	CryoEM structure of the outer membrane secretin channel pIV from the f1 filamentous bacteriophage
title_full_unstemmed	CryoEM structure of the outer membrane secretin channel pIV from the f1 filamentous bacteriophage
title_sort	cryoem structure of the outer membrane secretin channel piv from the f1 filamentous bacteriophage
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/f71d9956f4a9496997c3360054dba2c1
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CryoEM structure of the outer membrane secretin channel pIV from the f1 filamentous bacteriophage

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