Evaluation of mass spectrometry MS/MS spectra for the presence of isopeptide crosslinked peptides.

Isopeptide crosslinked proteins can be the product of transglutaminase or of exposure to organophosphorus toxicants (OP). Transglutaminase links glutamine to lysine with loss of ammonia. OP toxicants induce a link between glutamic acid and lysine with loss of water. Our goal was to establish criteri...

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Autores principales: Lawrence M Schopfer, Seda Onder, Oksana Lockridge
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/f71f9d78cba4493881187d548b22dde3
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