Remitting long-standing major depression in a multiple sclerosis patient with several concurrent conditions

Navzer D Sachinvala,1 Angeline Stergiou,2 Duane E Haines3,4 1Retired, US Department of Agriculture-Agricultural Research Service, New Orleans, LA 70124, USA; 2Department of Medicine, Fairfield Medical Center, Lancaster, OH 43130, USA; 3Department of Neurobiology and Anatomy, Wake Forest School of M...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Sachinvala ND, Stergiou A, Haines DE
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	Major depression multiple sclerosis craniopharyngioma euthymia dimethyl fumarate bupropion S-adenosylmethionine vitamin D3 Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/f7396c0eb72c4f0385a9d0cbaf586a81
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:f7396c0eb72c4f0385a9d0cbaf586a81
record_format	dspace
spelling	oai:doaj.org-article:f7396c0eb72c4f0385a9d0cbaf586a812021-12-02T00:08:32ZRemitting long-standing major depression in a multiple sclerosis patient with several concurrent conditions1178-2021https://doaj.org/article/f7396c0eb72c4f0385a9d0cbaf586a812018-10-01T00:00:00Zhttps://www.dovepress.com/remitting-long-standing-major-depression-in-a-multiple-sclerosis-patie-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Navzer D Sachinvala,1 Angeline Stergiou,2 Duane E Haines3,4 1Retired, US Department of Agriculture-Agricultural Research Service, New Orleans, LA 70124, USA; 2Department of Medicine, Fairfield Medical Center, Lancaster, OH 43130, USA; 3Department of Neurobiology and Anatomy, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA; 4Department of Neurobiology and Anatomy, The University of Mississippi Medical Center, Jackson, MS 39216, USA Abstract: In this report, we discuss the case of an multiple sclerosis (MS) patient, age 62, who learned to attain and sustain euthymia despite his ailments. He has Ehlers Danlos Syndrome (EDS), asthma, MS, urticaria, and major depression (MD). Despite thriving limitations, the patient is an accomplished scientist, who struggled for > twelve years to emerge from being confined to bed and wheel chair with MS, to walking with crutches, scuba diving, writing manuscripts, and living a positive life. Through former educators, he reacquired problem-solving habits to study the literature on his illnesses; keep records; try new therapies; and use pharmaceutical, nutritional, physical, and psychological methods to attain euthymia. With this inculcation, years later, he discovered that dimethyl fumarate (DMF) suppressed inflammation, cramping, urticaria, and asthma; and the combination of bupropion, S-adenosylmethionine (SAMe), vitamin-D3 (vit-D3), yoga, and self-hypnosis relieved MD. Then, after a 14-month respite, the patient, discovered that he had adult onset craniopharyngioma: a benign, recurring, epithelial tumor that grows from vestigial embryonic tissue (Rathke’s pouch) which formed the anterior pituitary. The tumor grows aggressively and causes surrounding tissue and function losses. It caused headaches, disorientation, bitemporal vision loss, among other problems. To emerge from this conundrum, the patient employed his relearned habits; the above antidepressant cocktail (bupropion, SAMe, and vit-D3); and with 30 fractionated stereotactic radiation treatments shrank his tumor and gained relief. This is a single case, and methods we discovered serendipitously may not work for other chronically ill patients. Consequently, we want to encourage such patients and their physicians to discuss their experiences in peer-reviewed domains so readers may acquire new perspectives that help individualize their care, and have productive contented lives. Keywords: craniopharyngioma, euthymia, dimethyl fumarate, bupropion, S-adenosylmethionine, vitamin D3Sachinvala NDStergiou AHaines DEDove Medical PressarticleMajor depressionmultiple sclerosiscraniopharyngiomaeuthymiadimethyl fumaratebupropionS-adenosylmethioninevitamin D3Neurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol Volume 14, Pp 2545-2550 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Major depression multiple sclerosis craniopharyngioma euthymia dimethyl fumarate bupropion S-adenosylmethionine vitamin D3 Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Major depression multiple sclerosis craniopharyngioma euthymia dimethyl fumarate bupropion S-adenosylmethionine vitamin D3 Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Sachinvala ND Stergiou A Haines DE Remitting long-standing major depression in a multiple sclerosis patient with several concurrent conditions
description	Navzer D Sachinvala,1 Angeline Stergiou,2 Duane E Haines3,4 1Retired, US Department of Agriculture-Agricultural Research Service, New Orleans, LA 70124, USA; 2Department of Medicine, Fairfield Medical Center, Lancaster, OH 43130, USA; 3Department of Neurobiology and Anatomy, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA; 4Department of Neurobiology and Anatomy, The University of Mississippi Medical Center, Jackson, MS 39216, USA Abstract: In this report, we discuss the case of an multiple sclerosis (MS) patient, age 62, who learned to attain and sustain euthymia despite his ailments. He has Ehlers Danlos Syndrome (EDS), asthma, MS, urticaria, and major depression (MD). Despite thriving limitations, the patient is an accomplished scientist, who struggled for > twelve years to emerge from being confined to bed and wheel chair with MS, to walking with crutches, scuba diving, writing manuscripts, and living a positive life. Through former educators, he reacquired problem-solving habits to study the literature on his illnesses; keep records; try new therapies; and use pharmaceutical, nutritional, physical, and psychological methods to attain euthymia. With this inculcation, years later, he discovered that dimethyl fumarate (DMF) suppressed inflammation, cramping, urticaria, and asthma; and the combination of bupropion, S-adenosylmethionine (SAMe), vitamin-D3 (vit-D3), yoga, and self-hypnosis relieved MD. Then, after a 14-month respite, the patient, discovered that he had adult onset craniopharyngioma: a benign, recurring, epithelial tumor that grows from vestigial embryonic tissue (Rathke’s pouch) which formed the anterior pituitary. The tumor grows aggressively and causes surrounding tissue and function losses. It caused headaches, disorientation, bitemporal vision loss, among other problems. To emerge from this conundrum, the patient employed his relearned habits; the above antidepressant cocktail (bupropion, SAMe, and vit-D3); and with 30 fractionated stereotactic radiation treatments shrank his tumor and gained relief. This is a single case, and methods we discovered serendipitously may not work for other chronically ill patients. Consequently, we want to encourage such patients and their physicians to discuss their experiences in peer-reviewed domains so readers may acquire new perspectives that help individualize their care, and have productive contented lives. Keywords: craniopharyngioma, euthymia, dimethyl fumarate, bupropion, S-adenosylmethionine, vitamin D3
format	article
author	Sachinvala ND Stergiou A Haines DE
author_facet	Sachinvala ND Stergiou A Haines DE
author_sort	Sachinvala ND
title	Remitting long-standing major depression in a multiple sclerosis patient with several concurrent conditions
title_short	Remitting long-standing major depression in a multiple sclerosis patient with several concurrent conditions
title_full	Remitting long-standing major depression in a multiple sclerosis patient with several concurrent conditions
title_fullStr	Remitting long-standing major depression in a multiple sclerosis patient with several concurrent conditions
title_full_unstemmed	Remitting long-standing major depression in a multiple sclerosis patient with several concurrent conditions
title_sort	remitting long-standing major depression in a multiple sclerosis patient with several concurrent conditions
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/f7396c0eb72c4f0385a9d0cbaf586a81
work_keys_str_mv	AT sachinvaland remittinglongstandingmajordepressioninamultiplesclerosispatientwithseveralconcurrentconditions AT stergioua remittinglongstandingmajordepressioninamultiplesclerosispatientwithseveralconcurrentconditions AT hainesde remittinglongstandingmajordepressioninamultiplesclerosispatientwithseveralconcurrentconditions
_version_	1718403960970149888

Remitting long-standing major depression in a multiple sclerosis patient with several concurrent conditions

Ejemplares similares