Multiple aspects of male germ cell development and interactions with Sertoli cells require inositol hexakisphosphate kinase-1

Abstract Inositol hexakisphosphate kinase-1 (IP6K1) is required for male fertility, but the underlying mechanisms have been elusive. Here, we report that IP6K1 is required for multiple aspects of male germ cell development. This development requires selective interactions between germ cells and Sert...

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Bibliographic Details
Main Authors: Chenglai Fu, Tomas Rojas, Alfred C. Chin, Weiwei Cheng, Isaac A. Bernstein, Lauren K. Albacarys, William W. Wright, Solomon H. Snyder
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
R
Q
Online Access:https://doaj.org/article/f739f70dc2034291be1474b5f19655c4
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