Studies on the Interactions of 3,11-Difluoro-6,8,13-trimethyl-8<i>H</i>-quino[4,3,2-<i>kl</i>]acridinium and Insulin with the Quadruplex-Forming Oligonucleotide Sequence a2 from the Insulin-Linked Polymorphic Region

Recently, several quadruplex-DNA-forming sequences have been identified in the insulin-linked polymorphic region (ILPR), which is a guanine-rich oligonucleotide sequence in the promoter region of insulin. The formation of this non-canonical quadruplex DNA (G4-DNA) has been shown to be involved in th...

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Autores principales: Peter Jonas Wickhorst, Heiko Ihmels, Thomas Paululat
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/f73d9c5a588145f1ae2e619e0e091ca6
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