Green synthesis of silver nanoparticles by Chrysanthemum morifolium Ramat. extract and their application in clinical ultrasound gel

Yan He,1 Zhiyun Du,1,2 Huibin Lv,1 Qianfa Jia,1 Zhikai Tang,1 Xi Zheng,1,3 Kun Zhang,1 Fenghua Zhao11Institute of Natural Medicine and Green Chemistry, School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou, People’s Republic of China; 2State Key L...

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Autores principales:	He Y, Du ZY, Lv HB, Jia QF, Tang ZK, Zheng X, Zhang K, Zhao FH
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2013
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/f73eff7657ed46aa8835914f4fb23b9c
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spelling	oai:doaj.org-article:f73eff7657ed46aa8835914f4fb23b9c2021-12-02T04:46:24ZGreen synthesis of silver nanoparticles by Chrysanthemum morifolium Ramat. extract and their application in clinical ultrasound gel1176-91141178-2013https://doaj.org/article/f73eff7657ed46aa8835914f4fb23b9c2013-05-01T00:00:00Zhttp://www.dovepress.com/green-synthesis-of-silver-nanoparticles-by-chrysanthemum-morifolium-ra-a12987https://doaj.org/toc/1176-9114https://doaj.org/toc/1178-2013Yan He,1 Zhiyun Du,1,2 Huibin Lv,1 Qianfa Jia,1 Zhikai Tang,1 Xi Zheng,1,3 Kun Zhang,1 Fenghua Zhao11Institute of Natural Medicine and Green Chemistry, School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou, People’s Republic of China; 2State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, People’s Republic of China; 3Susan Lehman Cullman Laboratory for Cancer Research, Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ, USAAbstract: Eco-friendly green synthesis with plant extracts plays a very important role in nanotechnology, without any harmful chemicals. In this report, the synthesis of water-soluble silver nanoparticles was developed by treating silver ions with Chrysanthemum morifolium Ramat. extract at room temperature. The effect of the extract on the formation of silver nanoparticles was characterized by ultraviolet and visible absorption spectroscopy, X-ray diffraction, transmission electron microscopy, and Fourier transform infrared spectroscopy. The ultraviolet and visible absorption spectroscopy results show a strong resonance centered on the surface of silver nanoparticles (AgNP) at 430 nm. The Fourier transform infrared spectroscopy spectral study demonstrates Chrysanthemum morifolium Ramat. extract acted as the reducing and stabilizing agent during the synthesis. The X-ray diffraction analysis confirmed that the synthesized AgNP are single crystallines, corresponding with the result of transmission electron microscopy. Water-soluble AgNP, with an approximate size of 20 nm–50 nm were also observed in the transmission electron microscopy image. The bactericidal properties of the synthesized AgNP were investigated using the agar-dilution method and the growth-inhibition test. The results show the AgNP had potent bactericidal activity on Staphylococcus aureus and Escherichia coli, as well as a strong antibacterial activity against gram-negative bacteria, as compared to gram-positive bacteria with a dose-dependent effect, thus providing a clinical ultrasound gel with bactericidal property for prevention of cross infections.Keywords: silver nanoparticles, green synthesis, Chrysanthemum morifolium Ramat., bactericidal activity, ultrasound gelHe YDu ZYLv HBJia QFTang ZKZheng XZhang KZhao FHDove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2013, Iss default, Pp 1809-1815 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 He Y Du ZY Lv HB Jia QF Tang ZK Zheng X Zhang K Zhao FH Green synthesis of silver nanoparticles by Chrysanthemum morifolium Ramat. extract and their application in clinical ultrasound gel
description	Yan He,1 Zhiyun Du,1,2 Huibin Lv,1 Qianfa Jia,1 Zhikai Tang,1 Xi Zheng,1,3 Kun Zhang,1 Fenghua Zhao11Institute of Natural Medicine and Green Chemistry, School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou, People’s Republic of China; 2State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, People’s Republic of China; 3Susan Lehman Cullman Laboratory for Cancer Research, Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ, USAAbstract: Eco-friendly green synthesis with plant extracts plays a very important role in nanotechnology, without any harmful chemicals. In this report, the synthesis of water-soluble silver nanoparticles was developed by treating silver ions with Chrysanthemum morifolium Ramat. extract at room temperature. The effect of the extract on the formation of silver nanoparticles was characterized by ultraviolet and visible absorption spectroscopy, X-ray diffraction, transmission electron microscopy, and Fourier transform infrared spectroscopy. The ultraviolet and visible absorption spectroscopy results show a strong resonance centered on the surface of silver nanoparticles (AgNP) at 430 nm. The Fourier transform infrared spectroscopy spectral study demonstrates Chrysanthemum morifolium Ramat. extract acted as the reducing and stabilizing agent during the synthesis. The X-ray diffraction analysis confirmed that the synthesized AgNP are single crystallines, corresponding with the result of transmission electron microscopy. Water-soluble AgNP, with an approximate size of 20 nm–50 nm were also observed in the transmission electron microscopy image. The bactericidal properties of the synthesized AgNP were investigated using the agar-dilution method and the growth-inhibition test. The results show the AgNP had potent bactericidal activity on Staphylococcus aureus and Escherichia coli, as well as a strong antibacterial activity against gram-negative bacteria, as compared to gram-positive bacteria with a dose-dependent effect, thus providing a clinical ultrasound gel with bactericidal property for prevention of cross infections.Keywords: silver nanoparticles, green synthesis, Chrysanthemum morifolium Ramat., bactericidal activity, ultrasound gel
format	article
author	He Y Du ZY Lv HB Jia QF Tang ZK Zheng X Zhang K Zhao FH
author_facet	He Y Du ZY Lv HB Jia QF Tang ZK Zheng X Zhang K Zhao FH
author_sort	He Y
title	Green synthesis of silver nanoparticles by Chrysanthemum morifolium Ramat. extract and their application in clinical ultrasound gel
title_short	Green synthesis of silver nanoparticles by Chrysanthemum morifolium Ramat. extract and their application in clinical ultrasound gel
title_full	Green synthesis of silver nanoparticles by Chrysanthemum morifolium Ramat. extract and their application in clinical ultrasound gel
title_fullStr	Green synthesis of silver nanoparticles by Chrysanthemum morifolium Ramat. extract and their application in clinical ultrasound gel
title_full_unstemmed	Green synthesis of silver nanoparticles by Chrysanthemum morifolium Ramat. extract and their application in clinical ultrasound gel
title_sort	green synthesis of silver nanoparticles by chrysanthemum morifolium ramat. extract and their application in clinical ultrasound gel
publisher	Dove Medical Press
publishDate	2013
url	https://doaj.org/article/f73eff7657ed46aa8835914f4fb23b9c
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Green synthesis of silver nanoparticles by Chrysanthemum morifolium Ramat. extract and their application in clinical ultrasound gel

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