Reduced adaptation of glutamatergic stress response is associated with pessimistic expectations in depression
Stress is a major risk for mental illness that is known to impact glutamate function in the medial prefrontal cortex (mPFC). Using magnetic resonance spectroscopy we find evidence for an adaptive mPFC glutamate response to stress in healthy adults that is notably impaired in patients with major depr...
Guardado en:
Autores principales: | Jessica A. Cooper, Makiah R. Nuutinen, Victoria M. Lawlor, Brittany A. M. DeVries, Elyssa M. Barrick, Shabnam Hossein, Daniel J. Cole, Chelsea V. Leonard, Emma C. Hahn, Andrew P. Teer, Grant S. Shields, George M. Slavich, Dost Ongur, J. Eric Jensen, Fei Du, Diego A. Pizzagalli, Michael T. Treadway |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/f76778c6be8941f0a384537e46ed9397 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Dogs are more pessimistic if their owners use two or more aversive training methods
por: Rachel A. Casey, et al.
Publicado: (2021) -
Elevated levels of the stress hormone, corticosterone, cause ‘pessimistic’ judgment bias in broiler chickens
por: Oluwaseun S. Iyasere, et al.
Publicado: (2017) -
Mask exposure during COVID-19 changes emotional face processing.
por: Elyssa M Barrick, et al.
Publicado: (2021) -
Novel glutamatergic drugs for the treatment of mood disorders
por: Murrough JW, et al.
Publicado: (2013) -
Role of nucleus accumbens glutamatergic plasticity in drug addiction
por: Quintero GC
Publicado: (2013)