Generation of mature compact ventricular cardiomyocytes from human pluripotent stem cells

Cardiomyocytes of heart ventricles consist of subpopulations of trabecular and compact subtypes. Here the authors describe the generation of structurally, metabolically and functionally mature compact ventricular cardiomyocytes as well as mature atrial cardiomyocytes from human pluripotent stem cell...

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Autores principales: Shunsuke Funakoshi, Ian Fernandes, Olya Mastikhina, Dan Wilkinson, Thinh Tran, Wahiba Dhahri, Amine Mazine, Donghe Yang, Benjamin Burnett, Jeehoon Lee, Stephanie Protze, Gary D. Bader, Sara S. Nunes, Michael Laflamme, Gordon Keller
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/f76e2fa406dd4238a8a294dc0fe7b884
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spelling oai:doaj.org-article:f76e2fa406dd4238a8a294dc0fe7b8842021-12-02T15:00:39ZGeneration of mature compact ventricular cardiomyocytes from human pluripotent stem cells10.1038/s41467-021-23329-z2041-1723https://doaj.org/article/f76e2fa406dd4238a8a294dc0fe7b8842021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23329-zhttps://doaj.org/toc/2041-1723Cardiomyocytes of heart ventricles consist of subpopulations of trabecular and compact subtypes. Here the authors describe the generation of structurally, metabolically and functionally mature compact ventricular cardiomyocytes as well as mature atrial cardiomyocytes from human pluripotent stem cells.Shunsuke FunakoshiIan FernandesOlya MastikhinaDan WilkinsonThinh TranWahiba DhahriAmine MazineDonghe YangBenjamin BurnettJeehoon LeeStephanie ProtzeGary D. BaderSara S. NunesMichael LaflammeGordon KellerNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-23 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Shunsuke Funakoshi
Ian Fernandes
Olya Mastikhina
Dan Wilkinson
Thinh Tran
Wahiba Dhahri
Amine Mazine
Donghe Yang
Benjamin Burnett
Jeehoon Lee
Stephanie Protze
Gary D. Bader
Sara S. Nunes
Michael Laflamme
Gordon Keller
Generation of mature compact ventricular cardiomyocytes from human pluripotent stem cells
description Cardiomyocytes of heart ventricles consist of subpopulations of trabecular and compact subtypes. Here the authors describe the generation of structurally, metabolically and functionally mature compact ventricular cardiomyocytes as well as mature atrial cardiomyocytes from human pluripotent stem cells.
format article
author Shunsuke Funakoshi
Ian Fernandes
Olya Mastikhina
Dan Wilkinson
Thinh Tran
Wahiba Dhahri
Amine Mazine
Donghe Yang
Benjamin Burnett
Jeehoon Lee
Stephanie Protze
Gary D. Bader
Sara S. Nunes
Michael Laflamme
Gordon Keller
author_facet Shunsuke Funakoshi
Ian Fernandes
Olya Mastikhina
Dan Wilkinson
Thinh Tran
Wahiba Dhahri
Amine Mazine
Donghe Yang
Benjamin Burnett
Jeehoon Lee
Stephanie Protze
Gary D. Bader
Sara S. Nunes
Michael Laflamme
Gordon Keller
author_sort Shunsuke Funakoshi
title Generation of mature compact ventricular cardiomyocytes from human pluripotent stem cells
title_short Generation of mature compact ventricular cardiomyocytes from human pluripotent stem cells
title_full Generation of mature compact ventricular cardiomyocytes from human pluripotent stem cells
title_fullStr Generation of mature compact ventricular cardiomyocytes from human pluripotent stem cells
title_full_unstemmed Generation of mature compact ventricular cardiomyocytes from human pluripotent stem cells
title_sort generation of mature compact ventricular cardiomyocytes from human pluripotent stem cells
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/f76e2fa406dd4238a8a294dc0fe7b884
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