Human commensal gut Proteobacteria withstand type VI secretion attacks through immunity protein-independent mechanisms

Here, the authors study the impact of Vibrio cholerae’s T6SS on human gut microbiota isolates and show that certain bacteria are protected from T6SS attacks in an immunity protein-independent manner. Specifically, protection occurred through superior T6SS weaponry in members of the Enterobacter cloa...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Nicolas Flaugnatti, Sandrine Isaac, Leonardo F. Lemos Rocha, Sandrine Stutzmann, Olaya Rendueles, Candice Stoudmann, Nina Vesel, Marc Garcia-Garcera, Amandine Buffet, Thibault G. Sana, Eduardo P. C. Rocha, Melanie Blokesch
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Q
Acceso en línea:https://doaj.org/article/f76f9f8adc3e4e19aaec1eaf0004848b
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:f76f9f8adc3e4e19aaec1eaf0004848b
record_format dspace
spelling oai:doaj.org-article:f76f9f8adc3e4e19aaec1eaf0004848b2021-12-02T19:16:51ZHuman commensal gut Proteobacteria withstand type VI secretion attacks through immunity protein-independent mechanisms10.1038/s41467-021-26041-02041-1723https://doaj.org/article/f76f9f8adc3e4e19aaec1eaf0004848b2021-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26041-0https://doaj.org/toc/2041-1723Here, the authors study the impact of Vibrio cholerae’s T6SS on human gut microbiota isolates and show that certain bacteria are protected from T6SS attacks in an immunity protein-independent manner. Specifically, protection occurred through superior T6SS weaponry in members of the Enterobacter cloacae complex and by molecular armors made of membrane-tethered capsular polysaccharides of diverse Klebsiella isolates.Nicolas FlaugnattiSandrine IsaacLeonardo F. Lemos RochaSandrine StutzmannOlaya RenduelesCandice StoudmannNina VeselMarc Garcia-GarceraAmandine BuffetThibault G. SanaEduardo P. C. RochaMelanie BlokeschNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Nicolas Flaugnatti
Sandrine Isaac
Leonardo F. Lemos Rocha
Sandrine Stutzmann
Olaya Rendueles
Candice Stoudmann
Nina Vesel
Marc Garcia-Garcera
Amandine Buffet
Thibault G. Sana
Eduardo P. C. Rocha
Melanie Blokesch
Human commensal gut Proteobacteria withstand type VI secretion attacks through immunity protein-independent mechanisms
description Here, the authors study the impact of Vibrio cholerae’s T6SS on human gut microbiota isolates and show that certain bacteria are protected from T6SS attacks in an immunity protein-independent manner. Specifically, protection occurred through superior T6SS weaponry in members of the Enterobacter cloacae complex and by molecular armors made of membrane-tethered capsular polysaccharides of diverse Klebsiella isolates.
format article
author Nicolas Flaugnatti
Sandrine Isaac
Leonardo F. Lemos Rocha
Sandrine Stutzmann
Olaya Rendueles
Candice Stoudmann
Nina Vesel
Marc Garcia-Garcera
Amandine Buffet
Thibault G. Sana
Eduardo P. C. Rocha
Melanie Blokesch
author_facet Nicolas Flaugnatti
Sandrine Isaac
Leonardo F. Lemos Rocha
Sandrine Stutzmann
Olaya Rendueles
Candice Stoudmann
Nina Vesel
Marc Garcia-Garcera
Amandine Buffet
Thibault G. Sana
Eduardo P. C. Rocha
Melanie Blokesch
author_sort Nicolas Flaugnatti
title Human commensal gut Proteobacteria withstand type VI secretion attacks through immunity protein-independent mechanisms
title_short Human commensal gut Proteobacteria withstand type VI secretion attacks through immunity protein-independent mechanisms
title_full Human commensal gut Proteobacteria withstand type VI secretion attacks through immunity protein-independent mechanisms
title_fullStr Human commensal gut Proteobacteria withstand type VI secretion attacks through immunity protein-independent mechanisms
title_full_unstemmed Human commensal gut Proteobacteria withstand type VI secretion attacks through immunity protein-independent mechanisms
title_sort human commensal gut proteobacteria withstand type vi secretion attacks through immunity protein-independent mechanisms
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/f76f9f8adc3e4e19aaec1eaf0004848b
work_keys_str_mv AT nicolasflaugnatti humancommensalgutproteobacteriawithstandtypevisecretionattacksthroughimmunityproteinindependentmechanisms
AT sandrineisaac humancommensalgutproteobacteriawithstandtypevisecretionattacksthroughimmunityproteinindependentmechanisms
AT leonardoflemosrocha humancommensalgutproteobacteriawithstandtypevisecretionattacksthroughimmunityproteinindependentmechanisms
AT sandrinestutzmann humancommensalgutproteobacteriawithstandtypevisecretionattacksthroughimmunityproteinindependentmechanisms
AT olayarendueles humancommensalgutproteobacteriawithstandtypevisecretionattacksthroughimmunityproteinindependentmechanisms
AT candicestoudmann humancommensalgutproteobacteriawithstandtypevisecretionattacksthroughimmunityproteinindependentmechanisms
AT ninavesel humancommensalgutproteobacteriawithstandtypevisecretionattacksthroughimmunityproteinindependentmechanisms
AT marcgarciagarcera humancommensalgutproteobacteriawithstandtypevisecretionattacksthroughimmunityproteinindependentmechanisms
AT amandinebuffet humancommensalgutproteobacteriawithstandtypevisecretionattacksthroughimmunityproteinindependentmechanisms
AT thibaultgsana humancommensalgutproteobacteriawithstandtypevisecretionattacksthroughimmunityproteinindependentmechanisms
AT eduardopcrocha humancommensalgutproteobacteriawithstandtypevisecretionattacksthroughimmunityproteinindependentmechanisms
AT melanieblokesch humancommensalgutproteobacteriawithstandtypevisecretionattacksthroughimmunityproteinindependentmechanisms
_version_ 1718376949424848896