Next-Generation Computationally Designed Influenza Hemagglutinin Vaccines Protect against H5Nx Virus Infections

H5N1 COBRA hemagglutinin (HA) sequences, termed human COBRA-2 HA, were constructed through layering of HA sequences from viruses isolated from humans collected between 2004–2007 using only clade 2 strains. These COBRA HA proteins, when expressed on the surface of virus-like particles (VLP), elicited...

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Bibliographic Details
Main Authors: Ivette A. Nuñez, Ying Huang, Ted M. Ross
Format: article
Language:EN
Published: MDPI AG 2021
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Online Access:https://doaj.org/article/f77127bfd75647069590b4e78ed1d0c3
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