Optical deciphering of multinary chiral compound mixtures through organic reaction based chemometric chirality sensing

The stereoselective analysis of mixtures of chiral compounds typically requires time-consuming chromatography. Here, the authors combine reaction based chiroptical sensing and chemometric tools to directly determine the absolute configuration, enantiomeric composition and concentration of convoluted...

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Autores principales: Diandra S. Hassan, Christian Wolf
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/f776e8645a98457c9ce2e889f93509fa
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spelling oai:doaj.org-article:f776e8645a98457c9ce2e889f93509fa2021-11-14T12:36:44ZOptical deciphering of multinary chiral compound mixtures through organic reaction based chemometric chirality sensing10.1038/s41467-021-26874-92041-1723https://doaj.org/article/f776e8645a98457c9ce2e889f93509fa2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26874-9https://doaj.org/toc/2041-1723The stereoselective analysis of mixtures of chiral compounds typically requires time-consuming chromatography. Here, the authors combine reaction based chiroptical sensing and chemometric tools to directly determine the absolute configuration, enantiomeric composition and concentration of convoluted samples without physical separation.Diandra S. HassanChristian WolfNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Diandra S. Hassan
Christian Wolf
Optical deciphering of multinary chiral compound mixtures through organic reaction based chemometric chirality sensing
description The stereoselective analysis of mixtures of chiral compounds typically requires time-consuming chromatography. Here, the authors combine reaction based chiroptical sensing and chemometric tools to directly determine the absolute configuration, enantiomeric composition and concentration of convoluted samples without physical separation.
format article
author Diandra S. Hassan
Christian Wolf
author_facet Diandra S. Hassan
Christian Wolf
author_sort Diandra S. Hassan
title Optical deciphering of multinary chiral compound mixtures through organic reaction based chemometric chirality sensing
title_short Optical deciphering of multinary chiral compound mixtures through organic reaction based chemometric chirality sensing
title_full Optical deciphering of multinary chiral compound mixtures through organic reaction based chemometric chirality sensing
title_fullStr Optical deciphering of multinary chiral compound mixtures through organic reaction based chemometric chirality sensing
title_full_unstemmed Optical deciphering of multinary chiral compound mixtures through organic reaction based chemometric chirality sensing
title_sort optical deciphering of multinary chiral compound mixtures through organic reaction based chemometric chirality sensing
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/f776e8645a98457c9ce2e889f93509fa
work_keys_str_mv AT diandrashassan opticaldecipheringofmultinarychiralcompoundmixturesthroughorganicreactionbasedchemometricchiralitysensing
AT christianwolf opticaldecipheringofmultinarychiralcompoundmixturesthroughorganicreactionbasedchemometricchiralitysensing
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