Optical deciphering of multinary chiral compound mixtures through organic reaction based chemometric chirality sensing
The stereoselective analysis of mixtures of chiral compounds typically requires time-consuming chromatography. Here, the authors combine reaction based chiroptical sensing and chemometric tools to directly determine the absolute configuration, enantiomeric composition and concentration of convoluted...
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Nature Portfolio
2021
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oai:doaj.org-article:f776e8645a98457c9ce2e889f93509fa2021-11-14T12:36:44ZOptical deciphering of multinary chiral compound mixtures through organic reaction based chemometric chirality sensing10.1038/s41467-021-26874-92041-1723https://doaj.org/article/f776e8645a98457c9ce2e889f93509fa2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26874-9https://doaj.org/toc/2041-1723The stereoselective analysis of mixtures of chiral compounds typically requires time-consuming chromatography. Here, the authors combine reaction based chiroptical sensing and chemometric tools to directly determine the absolute configuration, enantiomeric composition and concentration of convoluted samples without physical separation.Diandra S. HassanChristian WolfNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021) |
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Science Q Diandra S. Hassan Christian Wolf Optical deciphering of multinary chiral compound mixtures through organic reaction based chemometric chirality sensing |
description |
The stereoselective analysis of mixtures of chiral compounds typically requires time-consuming chromatography. Here, the authors combine reaction based chiroptical sensing and chemometric tools to directly determine the absolute configuration, enantiomeric composition and concentration of convoluted samples without physical separation. |
format |
article |
author |
Diandra S. Hassan Christian Wolf |
author_facet |
Diandra S. Hassan Christian Wolf |
author_sort |
Diandra S. Hassan |
title |
Optical deciphering of multinary chiral compound mixtures through organic reaction based chemometric chirality sensing |
title_short |
Optical deciphering of multinary chiral compound mixtures through organic reaction based chemometric chirality sensing |
title_full |
Optical deciphering of multinary chiral compound mixtures through organic reaction based chemometric chirality sensing |
title_fullStr |
Optical deciphering of multinary chiral compound mixtures through organic reaction based chemometric chirality sensing |
title_full_unstemmed |
Optical deciphering of multinary chiral compound mixtures through organic reaction based chemometric chirality sensing |
title_sort |
optical deciphering of multinary chiral compound mixtures through organic reaction based chemometric chirality sensing |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/f776e8645a98457c9ce2e889f93509fa |
work_keys_str_mv |
AT diandrashassan opticaldecipheringofmultinarychiralcompoundmixturesthroughorganicreactionbasedchemometricchiralitysensing AT christianwolf opticaldecipheringofmultinarychiralcompoundmixturesthroughorganicreactionbasedchemometricchiralitysensing |
_version_ |
1718429144703827968 |