Single cell RNA-seq and ATAC-seq analysis of cardiac progenitor cell transition states and lineage settlement

Cardiac progenitor cells (CPCs) form cardiomyocytes, pericytes, smooth muscle and endothelial cells during embryonic development. Here, the authors characterize mouse CPCs marked by Nkx2.5 and Isl1 from E7.5 to E9.5 by single cell RNA-seq and ATAC-seq, showing fate transitions involve distinct open...

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Autores principales:	Guangshuai Jia, Jens Preussner, Xi Chen, Stefan Guenther, Xuejun Yuan, Michail Yekelchyk, Carsten Kuenne, Mario Looso, Yonggang Zhou, Sarah Teichmann, Thomas Braun
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f7864042a18d4c6f9b5af4ce0b06ab0a
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spelling	oai:doaj.org-article:f7864042a18d4c6f9b5af4ce0b06ab0a2021-12-02T14:41:17ZSingle cell RNA-seq and ATAC-seq analysis of cardiac progenitor cell transition states and lineage settlement10.1038/s41467-018-07307-62041-1723https://doaj.org/article/f7864042a18d4c6f9b5af4ce0b06ab0a2018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07307-6https://doaj.org/toc/2041-1723Cardiac progenitor cells (CPCs) form cardiomyocytes, pericytes, smooth muscle and endothelial cells during embryonic development. Here, the authors characterize mouse CPCs marked by Nkx2.5 and Isl1 from E7.5 to E9.5 by single cell RNA-seq and ATAC-seq, showing fate transitions involve distinct open chromatin state.Guangshuai JiaJens PreussnerXi ChenStefan GuentherXuejun YuanMichail YekelchykCarsten KuenneMario LoosoYonggang ZhouSarah TeichmannThomas BraunNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Guangshuai Jia Jens Preussner Xi Chen Stefan Guenther Xuejun Yuan Michail Yekelchyk Carsten Kuenne Mario Looso Yonggang Zhou Sarah Teichmann Thomas Braun Single cell RNA-seq and ATAC-seq analysis of cardiac progenitor cell transition states and lineage settlement
description	Cardiac progenitor cells (CPCs) form cardiomyocytes, pericytes, smooth muscle and endothelial cells during embryonic development. Here, the authors characterize mouse CPCs marked by Nkx2.5 and Isl1 from E7.5 to E9.5 by single cell RNA-seq and ATAC-seq, showing fate transitions involve distinct open chromatin state.
format	article
author	Guangshuai Jia Jens Preussner Xi Chen Stefan Guenther Xuejun Yuan Michail Yekelchyk Carsten Kuenne Mario Looso Yonggang Zhou Sarah Teichmann Thomas Braun
author_facet	Guangshuai Jia Jens Preussner Xi Chen Stefan Guenther Xuejun Yuan Michail Yekelchyk Carsten Kuenne Mario Looso Yonggang Zhou Sarah Teichmann Thomas Braun
author_sort	Guangshuai Jia
title	Single cell RNA-seq and ATAC-seq analysis of cardiac progenitor cell transition states and lineage settlement
title_short	Single cell RNA-seq and ATAC-seq analysis of cardiac progenitor cell transition states and lineage settlement
title_full	Single cell RNA-seq and ATAC-seq analysis of cardiac progenitor cell transition states and lineage settlement
title_fullStr	Single cell RNA-seq and ATAC-seq analysis of cardiac progenitor cell transition states and lineage settlement
title_full_unstemmed	Single cell RNA-seq and ATAC-seq analysis of cardiac progenitor cell transition states and lineage settlement
title_sort	single cell rna-seq and atac-seq analysis of cardiac progenitor cell transition states and lineage settlement
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/f7864042a18d4c6f9b5af4ce0b06ab0a
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Single cell RNA-seq and ATAC-seq analysis of cardiac progenitor cell transition states and lineage settlement

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