CHARACTERSTICS OF IMMUNE EFFECT OF BEMITHYL IN CHRONIC HEPATITIS

Abstract. Introduction of bemithyl into combined therapy of patients suffering chronic hepatitis allows toachieve a noticeable hepatoprotective effect. Apparently it is realized due to direct hepatotropic influence as well as through immunomodulatory action of the preparation directed at cellular im...

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Autores principales:	S. V. Okovity, O. V. Ivanova, A. A. Boykova, N. M. Kalinina, N. I. Davydova, V. G. Radchenko, S. N. Shulenin
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	hepatitis bemithyl immunomodulatory action Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/f78bb58f221a46139c19c4e4212f887c
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spelling	oai:doaj.org-article:f78bb58f221a46139c19c4e4212f887c2021-11-18T08:03:41ZCHARACTERSTICS OF IMMUNE EFFECT OF BEMITHYL IN CHRONIC HEPATITIS1563-06252313-741X10.15789/1563-0625-2005-1-93-99https://doaj.org/article/f78bb58f221a46139c19c4e4212f887c2014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/445https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. Introduction of bemithyl into combined therapy of patients suffering chronic hepatitis allows toachieve a noticeable hepatoprotective effect. Apparently it is realized due to direct hepatotropic influence as well as through immunomodulatory action of the preparation directed at cellular immunity. At the same time, immunotropic action of bemithyl can be characterized as immunomodulatory one, which is confirmed by stimulation of T–cell immunity with some suppression of B–section and humoral immunity. An important factor of the immunotropic action of the drug is the absence of autoimmunization phenomena. Influence of bemithyl on macrophages section manifested by the decrease of liver tissue infiltration and simultaneous increase of blood monocyte count. At the same time, initial oxygen–dependent microbicidal activity of macrophages decreased a little, but stimulated indices increased. (Med. Immunol., 2005, vol.7, № 1, pp 93599)S. V. OkovityO. V. IvanovaA. A. BoykovaN. M. KalininaN. I. DavydovaV. G. RadchenkoS. N. ShuleninSPb RAACIarticlehepatitisbemithylimmunomodulatory actionImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 7, Iss 1, Pp 93-99 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	hepatitis bemithyl immunomodulatory action Immunologic diseases. Allergy RC581-607
spellingShingle	hepatitis bemithyl immunomodulatory action Immunologic diseases. Allergy RC581-607 S. V. Okovity O. V. Ivanova A. A. Boykova N. M. Kalinina N. I. Davydova V. G. Radchenko S. N. Shulenin CHARACTERSTICS OF IMMUNE EFFECT OF BEMITHYL IN CHRONIC HEPATITIS
description	Abstract. Introduction of bemithyl into combined therapy of patients suffering chronic hepatitis allows toachieve a noticeable hepatoprotective effect. Apparently it is realized due to direct hepatotropic influence as well as through immunomodulatory action of the preparation directed at cellular immunity. At the same time, immunotropic action of bemithyl can be characterized as immunomodulatory one, which is confirmed by stimulation of T–cell immunity with some suppression of B–section and humoral immunity. An important factor of the immunotropic action of the drug is the absence of autoimmunization phenomena. Influence of bemithyl on macrophages section manifested by the decrease of liver tissue infiltration and simultaneous increase of blood monocyte count. At the same time, initial oxygen–dependent microbicidal activity of macrophages decreased a little, but stimulated indices increased. (Med. Immunol., 2005, vol.7, № 1, pp 93599)
format	article
author	S. V. Okovity O. V. Ivanova A. A. Boykova N. M. Kalinina N. I. Davydova V. G. Radchenko S. N. Shulenin
author_facet	S. V. Okovity O. V. Ivanova A. A. Boykova N. M. Kalinina N. I. Davydova V. G. Radchenko S. N. Shulenin
author_sort	S. V. Okovity
title	CHARACTERSTICS OF IMMUNE EFFECT OF BEMITHYL IN CHRONIC HEPATITIS
title_short	CHARACTERSTICS OF IMMUNE EFFECT OF BEMITHYL IN CHRONIC HEPATITIS
title_full	CHARACTERSTICS OF IMMUNE EFFECT OF BEMITHYL IN CHRONIC HEPATITIS
title_fullStr	CHARACTERSTICS OF IMMUNE EFFECT OF BEMITHYL IN CHRONIC HEPATITIS
title_full_unstemmed	CHARACTERSTICS OF IMMUNE EFFECT OF BEMITHYL IN CHRONIC HEPATITIS
title_sort	characterstics of immune effect of bemithyl in chronic hepatitis
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/f78bb58f221a46139c19c4e4212f887c
work_keys_str_mv	AT svokovity charactersticsofimmuneeffectofbemithylinchronichepatitis AT ovivanova charactersticsofimmuneeffectofbemithylinchronichepatitis AT aaboykova charactersticsofimmuneeffectofbemithylinchronichepatitis AT nmkalinina charactersticsofimmuneeffectofbemithylinchronichepatitis AT nidavydova charactersticsofimmuneeffectofbemithylinchronichepatitis AT vgradchenko charactersticsofimmuneeffectofbemithylinchronichepatitis AT snshulenin charactersticsofimmuneeffectofbemithylinchronichepatitis
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CHARACTERSTICS OF IMMUNE EFFECT OF BEMITHYL IN CHRONIC HEPATITIS

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