Structural basis of transcobalamin recognition by human CD320 receptor

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Structural basis of transcobalamin recognition by human CD320 receptor

Cellular uptake of vitamin B12 (cobalamin) requires the binding of holo-transcobalamin (TC) from plasma by CD320. Here, the authors report the structure of a complex between CD320 and TC loaded with cyanocobalamin, alongside additional functional analysis.

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Détails bibliographiques
Auteurs principaux:	Amer Alam, Jae-Sung Woo, Jennifer Schmitz, Bernadette Prinz, Katharina Root, Fan Chen, Joël S. Bloch, Renato Zenobi, Kaspar P. Locher
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2016
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/f7968f92215d4073a761f286014aedaa
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

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