Autologous platelet concentrate in surgery for macular detachment associated with congenital optic disc pit

Jeroni Nadal,1,2 Marta S Figueroa,3 Elisa Carreras,2,4 Patricia Pujol,2,4 Maria Isabel Canut,2,4,5 Rafael Ignacio Barraquer2,6 1Vitreoretinal Surgery Department at Centro de Oftalmología Barraquer, 2Universitat autónoma de Barcelona, Barcelona, 3Vissum Madrid, Madrid, 4Institu...

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Autores principales:	Nadal J, Figueroa MS, Carreras E, Pujol P, Canut MI, Barraquer RI
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/f79746db64494d38a1a2d2911d2f8718
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spelling	oai:doaj.org-article:f79746db64494d38a1a2d2911d2f87182021-12-02T04:44:08ZAutologous platelet concentrate in surgery for macular detachment associated with congenital optic disc pit1177-5483https://doaj.org/article/f79746db64494d38a1a2d2911d2f87182015-10-01T00:00:00Zhttps://www.dovepress.com/autologous-platelet-concentrate-in-surgery-for-macular-detachment-asso-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Jeroni Nadal,1,2 Marta S Figueroa,3 Elisa Carreras,2,4 Patricia Pujol,2,4 Maria Isabel Canut,2,4,5 Rafael Ignacio Barraquer2,6 1Vitreoretinal Surgery Department at Centro de Oftalmología Barraquer, 2Universitat autónoma de Barcelona, Barcelona, 3Vissum Madrid, Madrid, 4Instituto Barraquer, 5Glaucoma Department at Centro de Oftalmología Barraquer, 6Cornea and Cataract Surgery Department at Centro de Oftalmología Barraquer, Barcelona, Spain Purpose: To evaluate the anatomical and functional results obtained with pars plana vitrectomy (PPV) plus autologous platelet concentrate (APC) as a treatment for macular detachment associated with optic disc pit (ODP).Methods: We performed a prospective interventional study of 19 eyes of 19 consecutive patients with posterior macular detachment due to ODP. All patients underwent PPV, posterior hyaloid peeling, fluid–air exchange, injection of 0.05 mL of APC over the ODP and 15% perfluoropropane (C3F8) endotamponade. Postoperative measures included face-up positioning for 2 hours and then avoidance of the face-up position during the ensuing 10 days. All patients underwent complete ophthalmologic examination and optical coherence tomography preoperatively at 1 month, 3 months, 6 months, 9 months, and 12 months postoperatively and then annually. Outcome measures were best corrected visual acuity (BCVA) by logMAR, improvement of quality of vision, macular attachment, and resolution of intraretinal schisis-like separation.Results: Preoperatively, the median BCVA was 0.70 (range: 0.30–1.70) and all patients showed improved visual acuity after surgery; BCVA was 0.22 (range: 0.07–0.52) at 12 months follow-up. All patients showed complete reabsorption of intraretinal fluid (median time: 3.5 months [range: 2–8 months]) and macular attachment at the end of follow-up (median: 60 months [range: 12–144 months]), with stable or improved visual acuity. No reoperations were needed and no major adverse events were recorded.Conclusion: For macular detachment associated with ODP, the combination of PPV, posterior hyaloid peeling, APC, and C3F8 tamponade is a highly effective alternative technique with stable anatomical and functional results. Keywords: macular detachment, optic disc pit, maculopathy, retinoschisis, pars plana vitrectomy, autologous platelet concentrateNadal JFigueroa MSCarreras EPujol PCanut MIBarraquer RIDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2015, Iss default, Pp 1965-1971 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Nadal J Figueroa MS Carreras E Pujol P Canut MI Barraquer RI Autologous platelet concentrate in surgery for macular detachment associated with congenital optic disc pit
description	Jeroni Nadal,1,2 Marta S Figueroa,3 Elisa Carreras,2,4 Patricia Pujol,2,4 Maria Isabel Canut,2,4,5 Rafael Ignacio Barraquer2,6 1Vitreoretinal Surgery Department at Centro de Oftalmología Barraquer, 2Universitat autónoma de Barcelona, Barcelona, 3Vissum Madrid, Madrid, 4Instituto Barraquer, 5Glaucoma Department at Centro de Oftalmología Barraquer, 6Cornea and Cataract Surgery Department at Centro de Oftalmología Barraquer, Barcelona, Spain Purpose: To evaluate the anatomical and functional results obtained with pars plana vitrectomy (PPV) plus autologous platelet concentrate (APC) as a treatment for macular detachment associated with optic disc pit (ODP).Methods: We performed a prospective interventional study of 19 eyes of 19 consecutive patients with posterior macular detachment due to ODP. All patients underwent PPV, posterior hyaloid peeling, fluid–air exchange, injection of 0.05 mL of APC over the ODP and 15% perfluoropropane (C3F8) endotamponade. Postoperative measures included face-up positioning for 2 hours and then avoidance of the face-up position during the ensuing 10 days. All patients underwent complete ophthalmologic examination and optical coherence tomography preoperatively at 1 month, 3 months, 6 months, 9 months, and 12 months postoperatively and then annually. Outcome measures were best corrected visual acuity (BCVA) by logMAR, improvement of quality of vision, macular attachment, and resolution of intraretinal schisis-like separation.Results: Preoperatively, the median BCVA was 0.70 (range: 0.30–1.70) and all patients showed improved visual acuity after surgery; BCVA was 0.22 (range: 0.07–0.52) at 12 months follow-up. All patients showed complete reabsorption of intraretinal fluid (median time: 3.5 months [range: 2–8 months]) and macular attachment at the end of follow-up (median: 60 months [range: 12–144 months]), with stable or improved visual acuity. No reoperations were needed and no major adverse events were recorded.Conclusion: For macular detachment associated with ODP, the combination of PPV, posterior hyaloid peeling, APC, and C3F8 tamponade is a highly effective alternative technique with stable anatomical and functional results. Keywords: macular detachment, optic disc pit, maculopathy, retinoschisis, pars plana vitrectomy, autologous platelet concentrate
format	article
author	Nadal J Figueroa MS Carreras E Pujol P Canut MI Barraquer RI
author_facet	Nadal J Figueroa MS Carreras E Pujol P Canut MI Barraquer RI
author_sort	Nadal J
title	Autologous platelet concentrate in surgery for macular detachment associated with congenital optic disc pit
title_short	Autologous platelet concentrate in surgery for macular detachment associated with congenital optic disc pit
title_full	Autologous platelet concentrate in surgery for macular detachment associated with congenital optic disc pit
title_fullStr	Autologous platelet concentrate in surgery for macular detachment associated with congenital optic disc pit
title_full_unstemmed	Autologous platelet concentrate in surgery for macular detachment associated with congenital optic disc pit
title_sort	autologous platelet concentrate in surgery for macular detachment associated with congenital optic disc pit
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/f79746db64494d38a1a2d2911d2f8718
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Autologous platelet concentrate in surgery for macular detachment associated with congenital optic disc pit

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