Dysregulation of mCD46 and sCD46 contribute to the pathogenesis of bullous pemphigoid

Dysregulation of mCD46 and sCD46 contribute to the pathogenesis of bullous pemphigoid

Abstract Bullous pemphigoid (BP) is an autoimmune bullous disease caused by autoantibodies against BP180 in the epidermal basement membrane. Autoantibody-mediated complement activation is an important process in BP pathogenesis. CD46, a crucial complement regulatory protein in the complement activat...

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Autores principales: Pei Qiao, Erle Dang, Tianyu Cao, Hui Fang, Jieyu Zhang, Hongjiang Qiao, Gang Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/f799adc11c2a48b79954883d0b0549c2
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