Induction of ROS and DNA damage-dependent senescence by icaritin contributes to its antitumor activity in hepatocellular carcinoma cells
Context: Icaritin (ICT), a prenylflavonoid derivative extracted from the Epimedium (Berberidaceae) genus, has been identified to exhibit antitumor effect in hepatocellular carcinoma (HCC) cells by inducing apoptosis. However, its effect on cellular senescence has not been elucidated. Objective: To i...
Guardado en:
Autores principales: | Shikang Wang, Qian Wang, Huijun Wang, Chengkun Qin, Xianping Cui, Lei Li, Yongqing Liu, Hong Chang |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Taylor & Francis Group
2019
|
Materias: | |
Acceso en línea: | https://doaj.org/article/f79c3d14159b4dc688de7db384be0069 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
The antioxidative defense system is involved in the premature senescence in transgenic tobacco (Nicotiana tabacum NC89)
por: Liu,Yu, et al.
Publicado: (2016) -
Overcoming the senescence‐associated secretory phenotype (SASP): a complex mechanism of resistance in the treatment of cancer
por: Cecilia R. Chambers, et al.
Publicado: (2021) -
Comprehensive Analysis Uncovers Prognostic and Immunogenic Characteristics of Cellular Senescence for Lung Adenocarcinoma
por: Weihao Lin, et al.
Publicado: (2021) -
The Dual Role of Senescence in Tumorigenesis
por: Chuaire-Noack,Lilian, et al.
Publicado: (2010) -
Targeting Mitochondrial Metabolism as a Strategy to Treat Senescence
por: Yun Haeng Lee, et al.
Publicado: (2021)