Dual origin of relapses in retinoic-acid resistant acute promyelocytic leukemia
Historical acute promyelocytic leukemia patients treated with retinoic acid and chemotherapy sometimes did relapse. Here the authors performed exome sequencing on 64 patient's samples from diagnosis/relapse/remission and show relapse associates either with cooperating oncogenes at diagnosis, or...
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Main Authors: | , , , , , , , , , , , , , |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2018
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Subjects: | |
Online Access: | https://doaj.org/article/f7a3de80783f451da9d5fe9382b1bfea |
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