The neonatal microbiome in utero and beyond: perinatal influences and long-term impacts

The neonatal microbiome offers a valuable model for studying the origins of human health and disease. As the field of metagenomics expands, we also increase our understanding of early life influences on its development. In this review we will describe common techniques used to define and measure the...

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Autores principales: Hill Lee, Sharma Ruchika, Hart Lara, Popov Jelena, Moshkovich Michal, Pai Nikhil
Formato: article
Lenguaje:EN
Publicado: De Gruyter 2021
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Acceso en línea:https://doaj.org/article/f7a4704bccb342c3a9b68b11dd1124fa
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spelling oai:doaj.org-article:f7a4704bccb342c3a9b68b11dd1124fa2021-12-05T14:10:52ZThe neonatal microbiome in utero and beyond: perinatal influences and long-term impacts2567-94302567-944910.1515/labmed-2021-0131https://doaj.org/article/f7a4704bccb342c3a9b68b11dd1124fa2021-12-01T00:00:00Zhttps://doi.org/10.1515/labmed-2021-0131https://doaj.org/toc/2567-9430https://doaj.org/toc/2567-9449The neonatal microbiome offers a valuable model for studying the origins of human health and disease. As the field of metagenomics expands, we also increase our understanding of early life influences on its development. In this review we will describe common techniques used to define and measure the microbiome. We will review in utero influences, normal perinatal development, and known risk factors for abnormal neonatal microbiome development. Finally, we will summarize current evidence that links early life microbial impacts on the development of chronic inflammatory diseases, obesity, and atopy.Hill LeeSharma RuchikaHart LaraPopov JelenaMoshkovich MichalPai NikhilDe GruyterarticleantenataldysbiosismicrobiomemicrobiotaneonatepretermMedical technologyR855-855.5ENJournal of Laboratory Medicine, Vol 45, Iss 6, Pp 275-291 (2021)
institution DOAJ
collection DOAJ
language EN
topic antenatal
dysbiosis
microbiome
microbiota
neonate
preterm
Medical technology
R855-855.5
spellingShingle antenatal
dysbiosis
microbiome
microbiota
neonate
preterm
Medical technology
R855-855.5
Hill Lee
Sharma Ruchika
Hart Lara
Popov Jelena
Moshkovich Michal
Pai Nikhil
The neonatal microbiome in utero and beyond: perinatal influences and long-term impacts
description The neonatal microbiome offers a valuable model for studying the origins of human health and disease. As the field of metagenomics expands, we also increase our understanding of early life influences on its development. In this review we will describe common techniques used to define and measure the microbiome. We will review in utero influences, normal perinatal development, and known risk factors for abnormal neonatal microbiome development. Finally, we will summarize current evidence that links early life microbial impacts on the development of chronic inflammatory diseases, obesity, and atopy.
format article
author Hill Lee
Sharma Ruchika
Hart Lara
Popov Jelena
Moshkovich Michal
Pai Nikhil
author_facet Hill Lee
Sharma Ruchika
Hart Lara
Popov Jelena
Moshkovich Michal
Pai Nikhil
author_sort Hill Lee
title The neonatal microbiome in utero and beyond: perinatal influences and long-term impacts
title_short The neonatal microbiome in utero and beyond: perinatal influences and long-term impacts
title_full The neonatal microbiome in utero and beyond: perinatal influences and long-term impacts
title_fullStr The neonatal microbiome in utero and beyond: perinatal influences and long-term impacts
title_full_unstemmed The neonatal microbiome in utero and beyond: perinatal influences and long-term impacts
title_sort neonatal microbiome in utero and beyond: perinatal influences and long-term impacts
publisher De Gruyter
publishDate 2021
url https://doaj.org/article/f7a4704bccb342c3a9b68b11dd1124fa
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