Single-molecule imaging reveals modulation of cell wall synthesis dynamics in live bacterial cells

The bacterial cell wall is important for cell shape and stability, but how the activities of the biosynthetic machinery are coordinated are not clear. Here the authors use single-molecule imaging and chemical perturbations to determine factors that affect the localization dynamics of penicillin-bind...

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Autores principales:	Timothy K. Lee, Kevin Meng, Handuo Shi, Kerwyn Casey Huang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f7a4d8ae5c9b480e83c2b8ff44dde880
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spelling	oai:doaj.org-article:f7a4d8ae5c9b480e83c2b8ff44dde8802021-12-02T16:58:12ZSingle-molecule imaging reveals modulation of cell wall synthesis dynamics in live bacterial cells10.1038/ncomms131702041-1723https://doaj.org/article/f7a4d8ae5c9b480e83c2b8ff44dde8802016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms13170https://doaj.org/toc/2041-1723The bacterial cell wall is important for cell shape and stability, but how the activities of the biosynthetic machinery are coordinated are not clear. Here the authors use single-molecule imaging and chemical perturbations to determine factors that affect the localization dynamics of penicillin-binding proteins (PBP)1A and PBP1B.Timothy K. LeeKevin MengHanduo ShiKerwyn Casey HuangNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Timothy K. Lee Kevin Meng Handuo Shi Kerwyn Casey Huang Single-molecule imaging reveals modulation of cell wall synthesis dynamics in live bacterial cells
description	The bacterial cell wall is important for cell shape and stability, but how the activities of the biosynthetic machinery are coordinated are not clear. Here the authors use single-molecule imaging and chemical perturbations to determine factors that affect the localization dynamics of penicillin-binding proteins (PBP)1A and PBP1B.
format	article
author	Timothy K. Lee Kevin Meng Handuo Shi Kerwyn Casey Huang
author_facet	Timothy K. Lee Kevin Meng Handuo Shi Kerwyn Casey Huang
author_sort	Timothy K. Lee
title	Single-molecule imaging reveals modulation of cell wall synthesis dynamics in live bacterial cells
title_short	Single-molecule imaging reveals modulation of cell wall synthesis dynamics in live bacterial cells
title_full	Single-molecule imaging reveals modulation of cell wall synthesis dynamics in live bacterial cells
title_fullStr	Single-molecule imaging reveals modulation of cell wall synthesis dynamics in live bacterial cells
title_full_unstemmed	Single-molecule imaging reveals modulation of cell wall synthesis dynamics in live bacterial cells
title_sort	single-molecule imaging reveals modulation of cell wall synthesis dynamics in live bacterial cells
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/f7a4d8ae5c9b480e83c2b8ff44dde880
work_keys_str_mv	AT timothyklee singlemoleculeimagingrevealsmodulationofcellwallsynthesisdynamicsinlivebacterialcells AT kevinmeng singlemoleculeimagingrevealsmodulationofcellwallsynthesisdynamicsinlivebacterialcells AT handuoshi singlemoleculeimagingrevealsmodulationofcellwallsynthesisdynamicsinlivebacterialcells AT kerwyncaseyhuang singlemoleculeimagingrevealsmodulationofcellwallsynthesisdynamicsinlivebacterialcells
_version_	1718382424097816576

Single-molecule imaging reveals modulation of cell wall synthesis dynamics in live bacterial cells

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