Multiparametric characterization of white matter alterations in early stage Huntington disease

Abstract Huntington’s disease (HD) is a monogenic, fully penetrant neurodegenerative disorder. Widespread white matter damage affects the brain of patients with HD at very early stages of the disease. Fixel-based analysis (FBA) is a novel method to investigate the contribution of individual crossing...

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Auteurs principaux: Isaac M. Adanyeguh, Francesca Branzoli, Cécile Delorme, Aurélie Méneret, Marie-Lorraine Monin, Marie-Pierre Luton, Alexandra Durr, Emanoel Sabidussi, Fanny Mochel
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/f7abda06509c4ea3a642f325b6131684
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