Common microRNA signatures in cardiac hypertrophic and atrophic remodeling induced by changes in hemodynamic load.
<h4>Background</h4>Mechanical overload leads to cardiac hypertrophy and mechanical unloading to cardiac atrophy. Both conditions produce similar transcriptional changes including a re-expression of fetal genes, despite obvious differences in phenotype. MicroRNAs (miRNAs) are discussed as...
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Auteurs principaux: | Ali El-Armouche, Alexander Peter Schwoerer, Christiane Neuber, Julius Emons, Daniel Biermann, Thomas Christalla, Adam Grundhoff, Thomas Eschenhagen, Wolfram Hubertus Zimmermann, Heimo Ehmke |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2010
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Sujets: | |
Accès en ligne: | https://doaj.org/article/f7b34f21c2c045f49d98f65bbcbf7772 |
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